Reviewed, UniProtKB/Swiss-Prot Q89L02 (SURE_BRAJA)

Names and origin

Protein names

Recommended name:
    5'-nucleotidase surE
    EC=3.1.3.5
Alternative name(s):
    Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	bll4746

Organism

Bradyrhizobium japonicum [Complete proteome] [HAMAP]

Taxonomic identifier

375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity.
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 255	255	5'-nucleotidase surE HAMAP MF_00060		PRO_0000111793
Sites
	Metal binding	8	1	Divalent metal cation By similarity
	Metal binding	9	1	Divalent metal cation By similarity
	Metal binding	40	1	Divalent metal cation By similarity
	Metal binding	93	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q89L02-1 [UniParc]. Last modified December 15, 2003. Version 2. Checksum: A0C53D4EBC78C760	FASTA	255	27,898
	10 20 30 40 50 60 MRILCTNDDG IHAPGLKVVE EIARALSDDV WVVAPELDQS GVSHSLSLND PLRLREVGPR 70 80 90 100 110 120 HFAVRGTPTD CVIMGARHIL GTKPPDLVLS GVNKGRNVAE DVVYSGTIAG ALEGTILGLP 130 140 150 160 170 180 SFALSQEFSV ETRERPPWDT ARTFGPDILR KVMAAGIPKE TVINVNFPSC APEDVLGIRV 190 200 210 220 230 240 TRQGKRNLGF LRIDERRDGR NNPYFWIGFE RAAMMDTPAE GTDLAALRER YVSVTPLRLD 250 RTNEAFSEAL GAALK

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000040 Genomic DNA. Translation: BAC50011.1. Different initiation.
RefSeq	NP_771386.1.
3D structure databases
HSSP	HSSP built from PDB template 1J9L based on UniProtKB P96112.
ModBase	Search...
Genome annotation databases
GeneID	1052297.
GenomeReviews	Gene locus bll4746 in contig BA000040_GR.
KEGG	bja:bll4746.
NMPDR	fig|224911.1.peg.4746.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q89L02.
Enzyme and pathway databases
BioCyc	BJAP224911:BLL4746-MON.
BRENDA	3.1.3.5. 280.
Family and domain databases
HAMAP	MF_00060. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
ProDom	PD005378. SurE. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00087. surE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_BRAJA

Accession

Primary (citable) accession number: Q89L02

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	December 15, 2003
Last modified:	June 16, 2009
This is version 39 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)