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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei69L-glutamineUniRule annotation1
Binding sitei214L-glutamineUniRule annotation1
Binding sitei233ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi37 – 39ATPUniRule annotation3
Nucleotide bindingi43 – 49ATPUniRule annotation7
Nucleotide bindingi263 – 264ATPUniRule annotation2
Nucleotide bindingi271 – 273ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:bll4837
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000002526 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001958261 – 558Glutamine--tRNA ligaseAdd BLAST558

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi224911.bll4837.

Structurei

3D structure databases

ProteinModelPortaliQ89KR6.
SMRiQ89KR6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi36 – 46"HIGH" regionUniRule annotationAdd BLAST11
Motifi270 – 274"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
InParanoidiQ89KR6.
KOiK01886.
OMAiVTHSICT.
OrthoDBiPOG091H00G9.
PhylomeDBiQ89KR6.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 3 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q89KR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEPVAAEVG RDFIRDIIQA DLDQAKYREI VTRFPPEPNG YLHIGHAKSI
60 70 80 90 100
ALNFGIAQEF PGRCHLRFDD TNPVKEEQEY IDSIQADVHW LGFDWGKNLF
110 120 130 140 150
FASDYFDRLY EWAETLIRDG LAYVDDQTQE EIRTSRGTLT EPGKNSPFRD
160 170 180 190 200
RSVDENLDLF RRMKAGEFPN GARVLRAKID MAAGNINLRD PVLYRILHAH
210 220 230 240 250
HPRTGNAWCI YPSYDYAHGQ SDAIEGITHS ICTLEFEDHR PLYDWFIEKL
260 270 280 290 300
PVPSKPHQYE FARLNLTYTL LSKRVLTQLV REGHVAGWDD PRMPTMAGMR
310 320 330 340 350
RRGVPPAALR EFVKRIGVAK ANSVVDVGML EFCIREELNR TAQRRMAVLK
360 370 380 390 400
PLKVVIENYP EGQTEELEAI NHPDDPSAGT RKITFGRELY IEQDDFMENP
410 420 430 440 450
PKKFFRLSPG NEVRLRYAYF VKCTGVIKNE SGEVVELRCT YDPATRGGNA
460 470 480 490 500
PDGRKVKATM HWLSAAASKP AEIRIYNQLF ANPSPDASNF AADLNPQSLE
510 520 530 540 550
ILSNARVEAS VAESNSTEPM QFERQGYFVR DKDSTPGKPV FSRTIGLRDT

FAKEVAKG
Length:558
Mass (Da):63,536
Last modified:June 1, 2003 - v1
Checksum:i71CA2AE1A8440845
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC50102.1.
RefSeqiNP_771477.1. NC_004463.1.
WP_011087605.1. NZ_CP011360.1.

Genome annotation databases

EnsemblBacteriaiBAC50102; BAC50102; BAC50102.
GeneIDi1052143.
KEGGibja:bll4837.
PATRICifig|224911.44.peg.4682.

Similar proteinsi

Entry informationi

Entry nameiSYQ_BRADU
AccessioniPrimary (citable) accession number: Q89KR6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: June 1, 2003
Last modified: August 30, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families