Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

NADH-quinone oxidoreductase subunit D

Gene

nuoD

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.UniRule annotation

Catalytic activityi

NADH + a quinone = NAD+ + a quinol.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
Biological processTransport
LigandNAD, Ubiquinone

Enzyme and pathway databases

BioCyciBDIA224911:G1G3J-4948-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-quinone oxidoreductase subunit DUniRule annotation (EC:1.6.5.11UniRule annotation)
Alternative name(s):
NADH dehydrogenase I subunit DUniRule annotation
NDH-1 subunit DUniRule annotation
Gene namesi
Name:nuoDUniRule annotation
Ordered Locus Names:bll4916
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000002526 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003577791 – 398NADH-quinone oxidoreductase subunit DAdd BLAST398

Keywords - PTMi

Quinone

Proteomic databases

PRIDEiQ89KI9

Interactioni

Subunit structurei

NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.UniRule annotation

Protein-protein interaction databases

STRINGi224911.bll4916

Structurei

3D structure databases

ProteinModelPortaliQ89KI9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 49 kDa subunit family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CQV Bacteria
COG0649 LUCA
HOGENOMiHOG000228264
InParanoidiQ89KI9
KOiK00333
OMAiKKIAWPA
OrthoDBiPOG091H08K1
PhylomeDBiQ89KI9

Family and domain databases

Gene3Di1.10.645.20, 1 hit
HAMAPiMF_01358 NDH1_NuoD, 1 hit
InterProiView protein in InterPro
IPR001135 NADH_Q_OxRdtase_suD
IPR038290 NADH_Q_OxRdtase_suD_sf
IPR014029 NADH_UbQ_OxRdtase_49kDa_CS
IPR022885 NDH1_su_D/H
IPR029014 NiFe-Hase_large
PfamiView protein in Pfam
PF00346 Complex1_49kDa, 1 hit
SUPFAMiSSF56762 SSF56762, 1 hit
TIGRFAMsiTIGR01962 NuoD, 1 hit
PROSITEiView protein in PROSITE
PS00535 COMPLEX1_49K, 1 hit

Sequencei

Sequence statusi: Complete.

Q89KI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEQPENLRN FTINFGPQHP AAHGVLRLVL ELDGEIVARV DPHIGLLHRG
60 70 80 90 100
TEKLIEQKTY LQAIPYFDRL DYVAPMNQEH AFCLAAEKLL GIEVPRRGQL
110 120 130 140 150
IRVLYCEIGR ILSHLLNVTT QAMDVGALTP PLWGFEEREK LMVFYERASG
160 170 180 190 200
SRMHAAFFRV GGVHQDLPQK LVDDIEAWCD PFLKVVDDLD RLLTANRIFK
210 220 230 240 250
QRNVDIGVVP LKEAWEWGFS GVMVRGSGAA WDLRKSQPYE CYAEMDFDIP
260 270 280 290 300
IGKNGDCYDR YLIRMEEMRQ SVRIMRQCIQ KLNAPEGKGP VVVEDNKVAP
310 320 330 340 350
PRRGEMKRSM EALIHHFKLY TEGVHVPAGE VYAAVEAPKG EFGVYLVADG
360 370 380 390
TNKPYKCKIR APGFAHLQAM DHICRGHLLA DVSAILGSLD IVFGEVDR
Length:398
Mass (Da):45,058
Last modified:June 1, 2003 - v1
Checksum:i9EF9233422304D86
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA Translation: BAC50181.1
RefSeqiNP_771556.1, NC_004463.1
WP_011087682.1, NZ_CP011360.1

Genome annotation databases

EnsemblBacteriaiBAC50181; BAC50181; BAC50181
GeneIDi1052040
KEGGibja:bll4916
PATRICifig|224911.44.peg.4766

Similar proteinsi

Entry informationi

Entry nameiNUOD_BRADU
AccessioniPrimary (citable) accession number: Q89KI9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health