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Q89HS7 (Q89HS7_BRAJA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine hydroxymethyltransferase 2 HAMAP MF_00051
Short name=SHMT 2 HAMAP MF_00051
Short name=Serine methylase 2 HAMAP MF_00051
EC=2.1.2.1 HAMAP MF_00051
Gene names
Name:glyA EMBL BAC51177.1
Synonyms:glyA2 HAMAP MF_00051
Ordered Locus Names:bll5912
OrganismBradyrhizobium japonicum
Taxonomic identifier375 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length460 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interconversion of serine and glycine By similarity. RuleBase RU000585 HAMAP MF_00051

Catalytic activity

5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. RuleBase RU000585 HAMAP MF_00051

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000585 HAMAP MF_00051

Pathway

One-carbon metabolism; tetrahydrofolate interconversion. HAMAP MF_00051

One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU000585

Subunit structure

Homotetramer By similarity. HAMAP MF_00051

Subcellular location

Cytoplasm By similarity HAMAP MF_00051.

Sequence similarities

Belongs to the SHMT family. RuleBase RU004104 HAMAP MF_00051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2631N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_00051

Sequences

Sequence LengthMass (Da)Tools
Q89HS7 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 6A05A7989EFE3A14

FASTA46049,927
        10         20         30         40         50         60 
MESTTVKREG FRRRSPGQPI CWKNSVLRSP SMPSFRNELS INDQEIAAAL VGEERRQQDG 

        70         80         90        100        110        120 
VELIPSENYT YPEVLELLGS VFTNKYSEGY PGRRYYGGQQ YTDEIERLAR ERACSLFRAE 

       130        140        150        160        170        180 
HANVQPLSGS PMNQAVYLGL LEPGDTILAM DLSHGGHLTH GAPVSHMGRL FNFIRYKTAP 

       190        200        210        220        230        240 
SNGGAIDFDE LRAIAREARP KMVLCGYSSY PRDLDYAAFK SIADEVGALT MADVSHYGGL 

       250        260        270        280        290        300 
VAANVMRNPL DAGFDVMTTT SHKTLRGPRG GIILCRKENA GRIDASVFPG LQGGPHMNVV 

       310        320        330        340        350        360 
AGIAVTLKKA ATSDFQVYAR QVLRNAKVLA GALMERGMKL VTDGTDNHMM VVDTAASVGL 

       370        380        390        400        410        420 
DGRAAEDVLD AIAITTNKQV IPDDPRPPLR PSGIRLGTPA ATTRGMGEPE MRRIGEFIAA 

       430        440        450        460 
ALQANGNDVV VARLRSECVE MCRAFPVPGV MSRANSVAKT

« Hide

References

[1]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USDA 110.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000040 Genomic DNA. Translation: BAC51177.1.
RefSeqNP_772552.1. NC_004463.1.

3D structure databases

HSSPHSSP built from PDB template 1LS3 based on UniProtKB P07511.
ProteinModelPortalQ89HS7.
SMRQ89HS7. Positions 38-443.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1055008.
GenomeReviewsGene locus bll5912 in contig BA000040_GR.
KEGGbja:bll5912.
NMPDRfig|224911.1.peg.5912.
PATRIC21195598. VBIBraJap65052_6034.

Phylogenomic databases

HOGENOMHBG301263.
OMAEVGDRIM.
PhylomeDBQ89HS7.
ProtClustDBCLSK911453.

Family and domain databases

HAMAPMF_00051. SHMT.
[Tree]
InterProIPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR001085. Ser_HO-MeTrfase.
IPR019798. Ser_HO-MeTrfase_PLP_BS.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
PANTHERPTHR11680. Gly_HO-Metrfase. 1 hit.
PfamPF00464. SHMT. 1 hit.
[Graphical view]
PIRSFPIRSF000412. SHMT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITEPS00096. SHMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ89HS7_BRAJA
AccessionPrimary (citable) accession number: Q89HS7
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: December 14, 2011
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info