ID   Q89HD9_BRADU            Unreviewed;       632 AA.
AC   Q89HD9;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 111.
DE   SubName: Full=Blr6052 protein {ECO:0000313|EMBL:BAC51317.1};
GN   OrderedLocusNames=blr6052 {ECO:0000313|EMBL:BAC51317.1};
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=224911 {ECO:0000313|EMBL:BAC51317.1, ECO:0000313|Proteomes:UP000002526};
RN   [1] {ECO:0000313|Proteomes:UP000002526}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110
RC   {ECO:0000313|Proteomes:UP000002526};
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; BA000040; BAC51317.1; -; Genomic_DNA.
DR   RefSeq; NP_772692.1; NC_004463.1.
DR   RefSeq; WP_011088793.1; NZ_CP011360.1.
DR   AlphaFoldDB; Q89HD9; -.
DR   STRING; 224911.AAV28_27790; -.
DR   EnsemblBacteria; BAC51317; BAC51317; BAC51317.
DR   GeneID; 64025817; -.
DR   KEGG; bja:blr6052; -.
DR   PATRIC; fig|224911.44.peg.6003; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_021956_0_0_5; -.
DR   InParanoid; Q89HD9; -.
DR   OrthoDB; 9789782at2; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IBA:GO_Central.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   CDD; cd12913; PDC1_MCP_like; 1.
DR   CDD; cd18774; PDC2_HK_sensor; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002526};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          449..581
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   632 AA;  68772 MW;  3C12D55A3C202350 CRC64;
     MFTFRTSITL AVMTFVVALA GLLIAIQARS LRAATHEAAS AFMDSASTKS LGRLQGELNA
     IASLVNVLAT SSSVADSNER SETGRAIPLF KAALQEMPQM DSIYAGFDNG AWLQVRRTSS
     LSEDQRDRLR APASAEFAIS LIRPTPAGDL PMRRVFQDRQ GNEVGEIDLW NYGYDGRKRS
     WYWQTLRSDR PYVSAPYLSF SIDAPVITVS APLRGKVPGV LAADLKLDTF SAFVQAQRPG
     QNGTVMIFDQ AGSLIAHPEF TGLVESAMTH PSQSQLPSID EINSGMVASV VRRSHNRDHN
     EGLIRDEDGQ GYLFRLTKFT LGEGYNGSIL LLAAEDDFVQ NVRRLQFTGL ILAIIVGAAF
     VPLVWMFGST MSHSLKRITA QAGQLQTLAE PSLAPVTSYI REIHELGSTV NLAQRAIWSF
     AHFVPKEIVR GLIDNSISTT LGGVKQEITL VFTDVQGFTT IAEAADPDGL MRQTSRYFSV
     MTDAFLTEGG TVDKFIGDAV MVFWNAPHPQ PDHVARACRA TLAAKAAGER LNAEFAAEGL
     TPFVTRFGIH VGEAVVGNVG SSERMNYTAL GNTVNLAARL EGLNKQVGTT VLASEDVYLR
     VRDQFEFKAF DAVIAKGMTK ETRIFELVGA SA
//