Q89H53 (ADEC2_BRAJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Adenine deaminase 2
Short name=Adenase 2
Short name=Adenine aminase 2
EC=3.5.4.2

Gene names

Name:	ade2
Ordered Locus Names:	bll6142

Organism

Bradyrhizobium japonicum

Taxonomic identifier

375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	625 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Adenine + H2O = hypoxanthine + NH3. HAMAP MF_01518
Cofactor	Manganese By similarity. HAMAP MF_01518
Sequence similarities	Belongs to the adenine deaminase family.

Ontologies

Keywords
Ligand	Manganese
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	adenine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	adenine deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 625	625	Adenine deaminase 2 HAMAP MF_01518		PRO_0000142408

Sequences

	Sequence		Length	Mass (Da)
	Q89H53 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 1C769BA03F284F8A	FASTA	625	69,695
	10 20 30 40 50 60 MRQVMNAIPD DLLITAPDEV RIRQDLVLTA LGHRPADRSL RVGRLLDVHS RTWSEDQEIV 70 80 90 100 110 120 IKGRRIAWVG PAGSYPGEVR ERVHRPDVAA VPGFGEVHKH IESSHLTPEW EAALVLPHGN 130 140 150 160 170 180 TWTCEASHEF SNVNGARNLE FWFEARRRGS PLKIFPQPGS AVPPTAYEWG GGWYGRDEQA 190 200 210 220 230 240 RFMAESLMVT GLDEVMDWPA VWNPDNPSYK RLWGMIEATF AARGVVEGHA SGLRDLPSIN 250 260 270 280 290 300 AFAAAGLASD HEVQTPEETW DKLTRGLFVE LRVYAMDEIV RWLLAKGLQD WSQIAFTTDD 310 320 330 340 350 360 RSASHTLELG ASDHNARLAI EAGLAPEIAI QCLTINPARH MRLTPFVGSL APGRFGDVVL 370 380 390 400 410 420 LSDVGKLTIA EVWADGVQIS EGERYIGQVP EIVWPDWATK TVNIKRSIKP QDFELRAEPG 430 440 450 460 470 480 RATMKAAVIR PFHWHPEFYT LELPVRDGAV QRDESEAITK FAIVDRFSGD GRIAKMFWRG 490 500 510 520 530 540 CGPRTPETAV ACSVAHDKHN IWVVGSSDAA MAKAVNALIE LQGGWALVRE GELVATVRFE 550 560 570 580 590 600 VGGLMSCRSA QALDAEMQAL YAEGRKVDWM YEPTYRPRWY PGFPERLMFA TLTCAPWSWV 610 620 LVAPCEQAPL GFINVQTGEA HPVIW

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000040 Genomic DNA. Translation: BAC51407.1.
RefSeq	NP_772782.1. NC_004463.1.
3D structure databases
ProteinModelPortal	Q89H53.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1050985.
GenomeReviews	Gene locus bll6142 in contig BA000040_GR.
KEGG	bja:bll6142.
NMPDR	fig|224911.1.peg.6142.
PATRIC	21196080. VBIBraJap65052_6275.
Phylogenomic databases
HOGENOM	HBG299229.
OMA	FAIVDRF.
PhylomeDB	Q89H53.
ProtClustDB	CLSK820086.
Enzyme and pathway databases
BioCyc	BJAP224911:BLL6142-MONOMER.
Family and domain databases
HAMAP	MF_01518. Adenine_deamin. [Tree]
InterPro	IPR006679. Adenine_deam. IPR006680. Amidohydro_1. IPR011059. Metal-dep_hydrolase_composite. [Graphical view]
KO	K01486.
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
SUPFAM	SSF51338. Metalo_hydrolase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ADEC2_BRAJA

Accession

Primary (citable) accession number: Q89H53

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2004
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program