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Protein

Adenine deaminase 2

Gene

ade2

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciBJAP224911:GJEJ-6189-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminase 2UniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
Adenase 2UniRule annotation
Short name:
Adenine aminase 2UniRule annotation
Gene namesi
Name:ade2UniRule annotation
Ordered Locus Names:bll6142
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000002526 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 625625Adenine deaminase 2PRO_0000142408Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224911.bll6142.

Structurei

3D structure databases

ProteinModelPortaliQ89H53.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000033812.
InParanoidiQ89H53.
KOiK01486.
OrthoDBiEOG622PNM.
PhylomeDBiQ89H53.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q89H53-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRQVMNAIPD DLLITAPDEV RIRQDLVLTA LGHRPADRSL RVGRLLDVHS
60 70 80 90 100
RTWSEDQEIV IKGRRIAWVG PAGSYPGEVR ERVHRPDVAA VPGFGEVHKH
110 120 130 140 150
IESSHLTPEW EAALVLPHGN TWTCEASHEF SNVNGARNLE FWFEARRRGS
160 170 180 190 200
PLKIFPQPGS AVPPTAYEWG GGWYGRDEQA RFMAESLMVT GLDEVMDWPA
210 220 230 240 250
VWNPDNPSYK RLWGMIEATF AARGVVEGHA SGLRDLPSIN AFAAAGLASD
260 270 280 290 300
HEVQTPEETW DKLTRGLFVE LRVYAMDEIV RWLLAKGLQD WSQIAFTTDD
310 320 330 340 350
RSASHTLELG ASDHNARLAI EAGLAPEIAI QCLTINPARH MRLTPFVGSL
360 370 380 390 400
APGRFGDVVL LSDVGKLTIA EVWADGVQIS EGERYIGQVP EIVWPDWATK
410 420 430 440 450
TVNIKRSIKP QDFELRAEPG RATMKAAVIR PFHWHPEFYT LELPVRDGAV
460 470 480 490 500
QRDESEAITK FAIVDRFSGD GRIAKMFWRG CGPRTPETAV ACSVAHDKHN
510 520 530 540 550
IWVVGSSDAA MAKAVNALIE LQGGWALVRE GELVATVRFE VGGLMSCRSA
560 570 580 590 600
QALDAEMQAL YAEGRKVDWM YEPTYRPRWY PGFPERLMFA TLTCAPWSWV
610 620
LVAPCEQAPL GFINVQTGEA HPVIW
Length:625
Mass (Da):69,695
Last modified:June 1, 2003 - v1
Checksum:i1C769BA03F284F8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC51407.1.
RefSeqiNP_772782.1. NC_004463.1.
WP_011088883.1. NC_004463.1.

Genome annotation databases

EnsemblBacteriaiBAC51407; BAC51407; BAC51407.
GeneIDi1050985.
KEGGibja:bll6142.
PATRICi21196080. VBIBraJap65052_6275.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC51407.1.
RefSeqiNP_772782.1. NC_004463.1.
WP_011088883.1. NC_004463.1.

3D structure databases

ProteinModelPortaliQ89H53.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224911.bll6142.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC51407; BAC51407; BAC51407.
GeneIDi1050985.
KEGGibja:bll6142.
PATRICi21196080. VBIBraJap65052_6275.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000033812.
InParanoidiQ89H53.
KOiK01486.
OrthoDBiEOG622PNM.
PhylomeDBiQ89H53.

Enzyme and pathway databases

BioCyciBJAP224911:GJEJ-6189-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110.

Entry informationi

Entry nameiADEC2_BRADU
AccessioniPrimary (citable) accession number: Q89H53
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: June 1, 2003
Last modified: February 17, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.