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Reviewed, UniProtKB/Swiss-Prot Q89FY1 (ASPD_BRAJA)

Last modified June 16, 2009. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable L-aspartate dehydrogenase
    EC=1.4.1.21
Gene names
Name: nadX
Ordered Locus Names: bll6567
OrganismBradyrhizobium japonicum [Complete proteome] [HAMAP]
Taxonomic identifier375 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity.

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity.

Sequence similarities

Belongs to the L-aspartate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 280280Probable L-aspartate dehydrogenase HAMAP MF_01265
PRO_0000144887

Sites

Active site2321 By similarity
Binding site1341NAD; via amide nitrogen By similarity
Binding site2021NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q89FY1-1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 545EC9E5ACBB4F75

FASTA28029,472
        10         20         30         40         50         60 
MDRRWKVMTD QTASSELRVA IAGLGSIGTK IAAALDQGEG LTLSAVAVRD PAKHQAFLNG 

        70         80         90        100        110        120 
LRRPPQVLPI DQLGEAADIV VECAPSSQLR AIVEPAVKRG KAAVVVSVGG LLDNFDLVDL 

       130        140        150        160        170        180 
ARANGGRIIV PTGALIGLDA VNAAVIGTIH SVKMVTRKPI DGLKGAPFIV HNNIDIDTLR 

       190        200        210        220        230        240 
EPLKLFEGTA REAAKGFPAN LNVAVALSLA GVGPDRTSVQ IWADPTVTRN VHRIEVEADS 

       250        260        270        280 
ARFSMSIENI PSENPKTGLI TALSVIALLR KQRATLCVGT 

« Hide

References

[1]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USDA 110.

Cross-references

Sequence databases

BA000040 Genomic DNA. Translation: BAC51832.1.
RefSeqNP_773207.1.

3D structure databases

HSSPHSSP built from PDB template 1H2H based on UniProtKB Q9X1X6.
ModBaseSearch...

Genome annotation databases

GeneID1050893.
GenomeReviewsGene locus bll6567 in contig BA000040_GR.
KEGGbja:bll6567.
NMPDRfig|224911.1.peg.6567.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ89FY1.
OMAQ89FY1. FPANLNV.

Enzyme and pathway databases

BioCycBJAP224911:BLL6567-MON.
BRENDA1.4.1.21. 280.

Family and domain databases

HAMAPMF_01265.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProDomPD017325. Asp_dh. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameASPD_BRAJA
AccessionPrimary (citable) accession number: Q89FY1
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: June 1, 2003
Last modified: June 16, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents