Q89FV4 (Q89FV4_BRAJA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-o-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase EMBL BAC51860.1

Gene names

Name:	lpxC EMBL BAC51860.1
Ordered Locus Names:	bll6595

Organism

Bradyrhizobium japonicum

Taxonomic identifier

375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	320 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q89FV4 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 9A786E01744379EE	FASTA	320	34,121
	10 20 30 40 50 60 MKFSRQTTLR AQATVVGVGV HSGLPVTLTL GPAPVDAGFV FVRTGLEGSD REVQATAEQV 70 80 90 100 110 120 IATDLATVLG DRDGPLVSTA EHVLAALRGM GVDNAAIEID GPEVPIMDGS AAAFIAAIEQ 130 140 150 160 170 180 AGIVTQPAQR RFIQVLKPIS VKIGDSFGEI RPHANGFRAE VEIDFANPVI GRQSYAFDLN 190 200 210 220 230 240 PERFRREVGR ARTFGLMCDV ARLWSAGYAL GASFDNTVVF DDERLLNTEG LRYADECVRH 250 260 270 280 290 300 KVLDVIGDLA LAGLPLLGAY RSVRGGHKLN HAVLTALLAD RTAWRVVEGE AVRRTTRPVA 310 320 ETGRGIVGGR IAAAYGPDVS

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000040 Genomic DNA. Translation: BAC51860.1.
RefSeq	NP_773235.1. NC_004463.1.
3D structure databases
HSSP	HSSP built from PDB template 1P42 based on UniProtKB O67648.
ProteinModelPortal	Q89FV4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1047780.
GenomeReviews	Gene locus bll6595 in contig BA000040_GR.
KEGG	bja:bll6595.
NMPDR	fig|224911.1.peg.6595.
PATRIC	21197036. VBIBraJap65052_6752.
Phylogenomic databases
HOGENOM	HBG482342.
OMA	KAYKSGH.
PhylomeDB	Q89FV4.
ProtClustDB	PRK13186.
Family and domain databases
HAMAP	MF_00388. LpxC. [Tree]
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
TIGRFAMs	TIGR00325. LpxC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q89FV4_BRAJA

Accession

Primary (citable) accession number: Q89FV4

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)