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Reviewed, UniProtKB/Swiss-Prot Q89FU9 (MURB_BRAJA)

Last modified February 9, 2010. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    UDP-N-acetylenolpyruvoylglucosamine reductase
    EC=1.1.1.158
Alternative name(s):
    UDP-N-acetylmuramate dehydrogenase
Gene names
Name: murB
Ordered Locus Names: bll6600
OrganismBradyrhizobium japonicum [Complete proteome] [HAMAP]
Taxonomic identifier375 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

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Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP MF_00037

Catalytic activity

UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH. HAMAP MF_00037

Cofactor

FAD By similarity. HAMAP MF_00037

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00037

Subcellular location

Cytoplasm Probable HAMAP MF_00037.

Sequence similarities

Belongs to the murB family.

Contains 1 FAD-binding PCMH-type domain.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 305305UDP-N-acetylenolpyruvoylglucosamine reductase HAMAP MF_00037
PRO_0000179184

Regions

Domain34 – 199166FAD-binding PCMH-type

Sites

Active site1791 By similarity
Active site2281Proton donor By similarity
Active site2981 By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q89FU9-1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 21D3DA57C925AED8

FASTA30532,228
        10         20         30         40         50         60 
MSFPDITPSL KATMPDLRGR LLANQSLAEL TWFRVGGPAQ VLFTPADEDD LAYFLAHLAS 

        70         80         90        100        110        120 
DIPVYVVGVG SNLIVRDGGI AGVVIRLAPR AFGEASASGD IVTAGAAALD KRVAEVAASA 

       130        140        150        160        170        180 
NIGGLEFYFG IPGTIGGALR MNAGANGGET KDVLIEARGV GRDGTKHVFS NADMKFVYRN 

       190        200        210        220        230        240 
SGVDPSIIFT SARFRGEVKD ADAIRARMAE VQSHRETAQP IREKTGGSTF KNPPGHSAWK 

       250        260        270        280        290        300 
LVDAAGCRGL RVGGAQVSEM HCNFLINTGD ATAHDIETLG ETVRARVKAN SGIELHWEIK 


RIGVS

« Hide

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References

[1]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USDA 110.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000040 Genomic DNA. Translation: BAC51865.1.
RefSeqNP_773240.1.

3D structure databases

SMRQ89FU9. Positions 22-300.
ModBaseSearch...

Genome annotation databases

GeneID1051152.
GenomeReviewsGene locus bll6600 in contig BA000040_GR.
KEGGbja:bll6600.
NMPDRfig|224911.1.peg.6600.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG686573.
OMAQPIREKT.

Enzyme and pathway databases

BioCycBJAP224911:BLL6600-MONOMER.
BRENDA1.1.1.158. 280.

Family and domain databases

HAMAPMF_00037. MurB.
[Tree]
InterProIPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR016167. FAD-bd_2_sub1.
IPR003170. MurB.
IPR011601. MurB_C.
IPR006094. Oxid_FAD_bind_N.
[Graphical view]
Gene3DG3DSA:3.30.465.10. CO_DH_flavoprot_FAD-bd_sub2. 1 hit.
G3DSA:3.30.43.10. FAD-binding_2_sub1. 1 hit.
G3DSA:3.90.78.10. MurB_C. 1 hit.
PANTHERPTHR21071. MurB. 1 hit.
PfamPF01565. FAD_binding_4. 1 hit.
PF02873. MurB_C. 1 hit.
[Graphical view]
TIGRFAMsTIGR00179. murB. 1 hit.
PROSITEPS51387. FAD_PCMH. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameMURB_BRAJA
AccessionPrimary (citable) accession number: Q89FU9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: February 9, 2010
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents