Skip Header

 
Contribute Send feedback

Reviewed, UniProtKB/Swiss-Prot Q89FG3 (PQQC_BRAJA)

Last modified November 4, 2008. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Pyrroloquinoline-quinone synthase
    EC=1.3.3.11
Alternative name(s):
    Coenzyme PQQ synthesis protein C
    Pyrroloquinoline quinone biosynthesis protein C
Gene names
Name: pqqC
Ordered Locus Names: blr6737
OrganismBradyrhizobium japonicum [Complete proteome] [HAMAP]
Taxonomic identifier375 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length259 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity.

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H(2)O(2) + 2 H(2)O.

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.

Sequence similarities

Belongs to the pqqC family.

Ontologies

Keywords

   Biological processPQQ biosynthesis
   Molecular functionOxidoreductase
   Technical termComplete proteome

Gene Ontology (GO)

   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

pyrroloquinoline quinone biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionpyrroloquinoline-quinone synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 259259Pyrroloquinoline-quinone synthase
PRO_0000219977

Sequences

Sequence LengthMass (Da)Tools
Q89FG3-1 [UniParc].

Last modified June 16, 2003. Version 1.
Checksum: 4D394C1ED932C30E

FASTA25929,290
        10         20         30         40         50         60 
MNAASLTGIT ALSIGKDIKL NSAEELEAAL RHIGATRYHS LHPFHKLLHG GKLNKGQVQA 

        70         80         90        100        110        120 
WALNRYYYQS TIPIKDAVVI SRFRDRATRL EWRHRIEDHD GDVGSEGGIE RWLKLTEGLG 

       130        140        150        160        170        180 
LDTAYVESTE GILPATRFAV EAYVHYCREK SPLEAIASSL TELFAPSIHE ERIAGMLQHY 

       190        200        210        220        230        240 
DFVNPDIMSY FKRRLTQAPR DANFALEYVR THARTPEERA SVCNALIFKT NVLWVQLDAL 

       250 
QHAYVEGHIP PGAFVPKEN 

« Hide

References

[1]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USDA 110.

Cross-references

Sequence databases

BA000040 Genomic DNA. Translation: BAC52002.1.
RefSeqNP_773377.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1049991.
GenomeReviewsGene locus blr6737 in contig BA000040_GR.
KEGGbja:blr6737.
NMPDRfig|224911.1.peg.6737.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ89FG3.

Enzyme and pathway databases

BioCycBJAP224911:BLR6737-MON.

Family and domain databases

HAMAPMF_00654.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synth_PqqC.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

Entry information

Entry namePQQC_BRAJA
AccessionPrimary (citable) accession number: Q89FG3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: June 16, 2003
Last modified: November 4, 2008
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents