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Q89FG3 (PQQC_BRAJA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroloquinoline-quinone synthase
EC=1.3.3.11
Alternative name(s):
Coenzyme PQQ synthesis protein C
Pyrroloquinoline quinone biosynthesis protein C
Gene names
Name:pqqC
Ordered Locus Names:blr6737
OrganismBradyrhizobium japonicum
Taxonomic identifier375 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length259 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654

Sequence similarities

Belongs to the pqqC family.

Ontologies

Keywords
   Biological processPQQ biosynthesis
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processpyrroloquinoline quinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionpyrroloquinoline-quinone synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 259259Pyrroloquinoline-quinone synthase HAMAP MF_00654
PRO_0000219977

Sequences

Sequence LengthMass (Da)Tools
Q89FG3 [UniParc].

Last modified June 16, 2003. Version 1.
Checksum: 4D394C1ED932C30E

FASTA25929,290
        10         20         30         40         50         60 
MNAASLTGIT ALSIGKDIKL NSAEELEAAL RHIGATRYHS LHPFHKLLHG GKLNKGQVQA 

        70         80         90        100        110        120 
WALNRYYYQS TIPIKDAVVI SRFRDRATRL EWRHRIEDHD GDVGSEGGIE RWLKLTEGLG 

       130        140        150        160        170        180 
LDTAYVESTE GILPATRFAV EAYVHYCREK SPLEAIASSL TELFAPSIHE ERIAGMLQHY 

       190        200        210        220        230        240 
DFVNPDIMSY FKRRLTQAPR DANFALEYVR THARTPEERA SVCNALIFKT NVLWVQLDAL 

       250 
QHAYVEGHIP PGAFVPKEN

« Hide

References

[1]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USDA 110.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000040 Genomic DNA. Translation: BAC52002.1.
RefSeqNP_773377.1. NC_004463.1.

3D structure databases

ProteinModelPortalQ89FG3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1049991.
GenomeReviewsGene locus blr6737 in contig BA000040_GR.
KEGGbja:blr6737.
NMPDRfig|224911.1.peg.6737.
PATRIC21197336. VBIBraJap65052_6902.

Phylogenomic databases

HOGENOMHBG288944.
OMAFRDRATR.
ProtClustDBPRK05157.

Enzyme and pathway databases

BioCycBJAP224911:BLR6737-MONOMER.

Family and domain databases

HAMAPMF_00654. PQQ_syn_PqqC.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synthPqqC_dom.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KOK06137.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMSSF48613. Heme_oxygenase. 1 hit.
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

Entry information

Entry namePQQC_BRAJA
AccessionPrimary (citable) accession number: Q89FG3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: June 16, 2003
Last modified: January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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