Reviewed, UniProtKB/Swiss-Prot Q89FG3 (PQQC_BRAJA)

Names and origin

Protein names

Recommended name:
    Pyrroloquinoline-quinone synthase
    EC=1.3.3.11
Alternative name(s):
    Coenzyme PQQ synthesis protein C
    Pyrroloquinoline quinone biosynthesis protein C

Gene names

Name:	pqqC
Ordered Locus Names:	blr6737

Organism

Bradyrhizobium japonicum [Complete proteome] [HAMAP]

Taxonomic identifier

375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	259 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity.
Catalytic activity	6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H(2)O(2) + 2 H(2)O.
Pathway	Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
Sequence similarities	Belongs to the pqqC family.

Ontologies

Keywords
Biological process	PQQ biosynthesis
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW pyrroloquinoline quinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	pyrroloquinoline-quinone synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 259	259	Pyrroloquinoline-quinone synthase		PRO_0000219977

Sequences

	Sequence		Length	Mass (Da)
	Q89FG3-1 [UniParc]. Last modified June 16, 2003. Version 1. Checksum: 4D394C1ED932C30E	FASTA	259	29,290
	10 20 30 40 50 60 MNAASLTGIT ALSIGKDIKL NSAEELEAAL RHIGATRYHS LHPFHKLLHG GKLNKGQVQA 70 80 90 100 110 120 WALNRYYYQS TIPIKDAVVI SRFRDRATRL EWRHRIEDHD GDVGSEGGIE RWLKLTEGLG 130 140 150 160 170 180 LDTAYVESTE GILPATRFAV EAYVHYCREK SPLEAIASSL TELFAPSIHE ERIAGMLQHY 190 200 210 220 230 240 DFVNPDIMSY FKRRLTQAPR DANFALEYVR THARTPEERA SVCNALIFKT NVLWVQLDAL 250 QHAYVEGHIP PGAFVPKEN

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000040 Genomic DNA. Translation: BAC52002.1.
RefSeq	NP_773377.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1049991.
GenomeReviews	Gene locus blr6737 in contig BA000040_GR.
KEGG	bja:blr6737.
NMPDR	fig|224911.1.peg.6737.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q89FG3.
Enzyme and pathway databases
BioCyc	BJAP224911:BLR6737-MON.
Family and domain databases
HAMAP	MF_00654. [Tree]
InterPro	IPR016084. Haem_Oase-like_multi-hlx. IPR011845. PQQ_synth_PqqC. IPR004305. TENA/THI4/PQQ_synth_PqqC. [Graphical view]
Gene3D	G3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
Pfam	PF03070. TENA_THI-4. 1 hit. [Graphical view]
TIGRFAMs	TIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PQQC_BRAJA

Accession

Primary (citable) accession number: Q89FG3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 16, 2003
Last sequence update:	June 16, 2003
Last modified:	November 4, 2008
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)