Reviewed, UniProtKB/Swiss-Prot Q89EM9 (MSRB_BRAJA)

Names and origin

Protein names

Recommended name:
    Peptide methionine sulfoxide reductase msrB
    EC=1.8.4.12
Alternative name(s):
    Peptide-methionine (R)-S-oxide reductase

Gene names

Name:	msrB
Ordered Locus Names:	blr7044

Organism

Bradyrhizobium japonicum [Complete proteome] [HAMAP]

Taxonomic identifier

375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	139 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity. HAMAP MF_01400
Sequence similarities	Belongs to the msrB Met sulfoxide reductase family.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 139	139	Peptide methionine sulfoxide reductase msrB HAMAP MF_01400		PRO_0000140263
Sites
	Active site	128	1	Nucleophile By similarity
	Metal binding	56	1	Zinc By similarity
	Metal binding	59	1	Zinc By similarity
	Metal binding	105	1	Zinc By similarity
	Metal binding	108	1	Zinc By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q89EM9-1 [UniParc]. Last modified June 16, 2003. Version 1. Checksum: 6B30220982D09E2A	FASTA	139	15,412
	10 20 30 40 50 60 MPDAKTKTTD DKVIKSEEQW RRELSPIQYA VLREKATERP FSGEYEHDHR AGTYVCAGCG 70 80 90 100 110 120 NVLFESDAKF DSGCGWPSFT QPAVESHVDE ERDVSHGMIR TEVLCAKCSG HLGHVFPDGP 130 GPTGLRYCIN SAALKLEPK

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000040 Genomic DNA. Translation: BAC52309.1.
RefSeq	NP_773684.1.
3D structure databases
SMR	Q89EM9. Positions 12-139.
ModBase	Search...
Genome annotation databases
GeneID	1047290.
GenomeReviews	Gene locus blr7044 in contig BA000040_GR.
KEGG	bja:blr7044.
NMPDR	fig|224911.1.peg.7044.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG715255.
OMA	KKGTERA.
PhylomeDB	Q89EM9.
Enzyme and pathway databases
BioCyc	BJAP224911:BLR7044-MONOMER.
BRENDA	1.8.4.12. 280.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
TIGRFAMs	TIGR00357. MsrB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSRB_BRAJA

Accession

Primary (citable) accession number: Q89EM9

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 16, 2003
Last sequence update:	June 16, 2003
Last modified:	February 9, 2010
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)