Reviewed, UniProtKB/Swiss-Prot Q89DN1 (GLMM_BRAJA)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	bll7408

Organism

Bradyrhizobium japonicum [Complete proteome] [HAMAP]

Taxonomic identifier

375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 447	447	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000147857
Sites
	Active site	101	1	Phosphoserine intermediate By similarity
	Metal binding	101	1	Magnesium; via phosphate group By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity
Amino acid modifications
	Modified residue	101	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q89DN1-1 [UniParc]. Last modified December 20, 2005. Version 2. Checksum: 84F3305329015F58	FASTA	447	48,276
	10 20 30 40 50 60 MSRKYFGTDG IRGRANGLIT PELALKVGQA AGLAFQRGDH RHRVVIGKDT RLSGYMIEYA 70 80 90 100 110 120 MVAGFTSVGM DVLLVGPMPT PAVAMLTKSM RADLGVMISA SHNLFEDNGI KLFGPQGFKL 130 140 150 160 170 180 SDDVEKQIEQ LLDEPIDKRL AQSASLGRAR RIDGVHDRYI EFAKRTLPRD LSLDGLRVVV 190 200 210 220 230 240 DCANGAAYKV VPEALWELGA DVVPIGVEPD GFNINKDCGS TSPEALSKKV REMRADIGIA 250 260 270 280 290 300 LDGDADRVIL VDERGHVVDG DQLLAVIAQS WKEDGRLSRP GIVATVMSNL GLERFLKGQG 310 320 330 340 350 360 LDLVRTPVGD RYVLEQMLSG GYNLGGEQSG HIILSDYATT GDGFVAALQV LAVVQKSRRP 370 380 390 400 410 420 VSEVCHRFDP LPQILKNVRH KGGKPLDDSD VKSAISDGEK RLNGHGRLLI RSSGTEPVIR 430 440 VMGEGEDRIL VEDVVDTIVS ALGQAAA

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000040 Genomic DNA. Translation: BAC52673.1. Different initiation.
RefSeq	NP_774048.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1049934.
GenomeReviews	Gene locus bll7408 in contig BA000040_GR.
KEGG	bja:bll7408.
NMPDR	fig|224911.1.peg.7408.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q89DN1.
Enzyme and pathway databases
BioCyc	BJAP224911:BLL7408-MON.
BRENDA	5.4.2.10. 280.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BRAJA

Accession

Primary (citable) accession number: Q89DN1

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	December 20, 2005
Last modified:	June 16, 2009
This is version 38 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)