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Protein

UvrABC system protein C

Gene

uvrC

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:blr7470
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000002526 Componenti: Chromosome

Subcellular locationi

Q89DG9:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002648751 – 686UvrABC system protein CAdd BLAST686

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi224911.blr7470.

Structurei

3D structure databases

ProteinModelPortaliQ89DG9.
SMRiQ89DG9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 160GIY-YIGUniRule annotationAdd BLAST80
Domaini270 – 305UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CII. Bacteria.
COG0322. LUCA.
HOGENOMiHOG000279961.
InParanoidiQ89DG9.
KOiK03703.
OMAiLFPIRQC.
OrthoDBiPOG091H01BS.
PhylomeDBiQ89DG9.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q89DG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHDSTDDPD DTRVRKSRRG TALDAPPQET APPDLDPATT GGDDEDDALL
60 70 80 90 100
PDILEESGAV GEEPLASGHE AIERAVRLAP TSPGVYRMLN ANADVLYVGK
110 120 130 140 150
AKNVKKRLSN YARQSAPQPA RILRMIAATV TVEIVSTNTE TEALLLEANL
160 170 180 190 200
IKQLRPRFNV QLRDDKSFPY ILITGDHWAP QILKHRGAQT RPGRYFGPFA
210 220 230 240 250
SAGAVNRTIT ALQRAFLIRS CTDSFFESRS RPCLLYQIRR CAGPCTREID
260 270 280 290 300
FPGYTTLVRE ATDFLSGKSH AVKQELAGEM EKAANELEFE TAALYRDRLA
310 320 330 340 350
ALSAIQSQQG INPRTVEEAD VFAIHQEGGF SCVEVFFFRT GQNWGNRAYF
360 370 380 390 400
PRAEKTFTPE EVLGSFLAQF YDDKPPPKNI LLSHEIEESE LLANALSIKA
410 420 430 440 450
GHKIEVTAPK RGEKKELVAH ALTNAREALG RKLADTATQG RLLDAMATTL
460 470 480 490 500
SLPHAPKRIE VYDNSHIQGT NAVGAMIVAG PDGFVKNQYR KFNIKSEGLT
510 520 530 540 550
PGDDYGMMRE VLERRFKRLI NPPEEGAKVK DDDFPQWPDL VIIDGGRGQL
560 570 580 590 600
NAVREIFANL GLTQVSLMSV AKGPDRDAGR ETLFMPEREA IKLEPRDPVL
610 620 630 640 650
YFIQRLRDEA HRFVIGSHRK LRKKDIREAG LQEIPGIGPS RKRALLHHFG
660 670 680
TLKEIERASI ADLGKVPGVS AESARRIFEY FHPQPG
Length:686
Mass (Da):76,253
Last modified:June 1, 2003 - v1
Checksum:i06BD0EF38BFE6ACB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC52735.1.
RefSeqiNP_774110.1. NC_004463.1.
WP_011090203.1. NZ_CP011360.1.

Genome annotation databases

EnsemblBacteriaiBAC52735; BAC52735; BAC52735.
GeneIDi1054260.
KEGGibja:blr7470.
PATRICifig|224911.44.peg.7569.

Similar proteinsi

Entry informationi

Entry nameiUVRC_BRADU
AccessioniPrimary (citable) accession number: Q89DG9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: June 1, 2003
Last modified: October 25, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families