Q89B29 (RSMD_BUCBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase D
EC=2.1.1.171

Alternative name(s):
16S rRNA m2G966 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase

Gene names

Name:	rsmD
Ordered Locus Names:	bbp_025

Organism

Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) [Complete proteome] [HAMAP]

Taxonomic identifier

224915 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 966 of 16S rRNA in the assembled 30S particle By similarity.
Catalytic activity	S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(966) in 16S rRNA.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmD family.

Ontologies

Keywords
Biological process	rRNA processing
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA methylation Inferred from electronic annotation. Source: InterPro
Molecular function	methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 196	196	Ribosomal RNA small subunit methyltransferase D		PRO_0000216244

Sequences

	Sequence		Length	Mass (Da)
	Q89B29 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 6967D74F4A27C737	FASTA	196	22,811
	10 20 30 40 50 60 MKILKKKSKI TSIQIISGKY KNSRIPIINT KNLRPTTNYI RETLFNWISN EKIKKSHCLD 70 80 90 100 110 120 CFSGSGALGI EAVSRYALSS TCIEIQKKAI FFLKKILIKL SITNVHVIRA NTIQWLKKPN 130 140 150 160 170 180 KSYDIIFLDP PFKTTLLKQT IALLIKNNWL KNNALIYIEQ ENTLNKLITP PNNWILKKEK 190 KTKKIHYSLY MNVNNF

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed: 12522265] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bp.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016826 Genomic DNA. Translation: AAO26768.1.
RefSeq	NP_777663.1. NC_004545.1.
3D structure databases
ProteinModelPortal	Q89B29.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000002455; EBBUCP00000002279; EBBUCG00000002455.
GeneID	1058366.
GenomeReviews	Gene locus bbp_025 in contig AE016826_GR.
KEGG	bab:bbp025.
PATRIC	21244821. VBIBucAph80364_0025.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000007785.
HOGENOM	HBG706795.
OMA	ISGQWRS.
PhylomeDB	Q89B29.
ProtClustDB	CLSK315008.
Enzyme and pathway databases
BioCyc	BAPH224915:BBP_025-MONOMER.
Family and domain databases
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. IPR004398. RNA_MeTrfase_RsmD. [Graphical view]
KO	K08316.
Pfam	PF03602. Cons_hypoth95. 1 hit. [Graphical view]
PIRSF	PIRSF004553. CHP00095. 1 hit.
TIGRFAMs	TIGR00095. TIGR00095. 1 hit.
PROSITE	PS00092. N6_MTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RSMD_BUCBP

Accession

Primary (citable) accession number: Q89B29

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program