Q89AV6 (SYGA_BUCBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	bbp_127

Organism

Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) [Complete proteome] [HAMAP]

Taxonomic identifier

224915 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 300	300	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_0000072832

Sequences

	Sequence		Length	Mass (Da)
	Q89AV6 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 537947BB79DDFEFE	FASTA	300	35,402
	10 20 30 40 50 60 MLSNFKKEKM NTSTTFYEII CTLEKYWHNQ NCTIIEPLDI SVGAGTFHNK TFFGTIGSKP 70 80 90 100 110 120 ISMAYVQSSR RPSDGRYGKN PNRLQHYYQF QVIIKPSPHN IQCLYLNSLK KLNIDCKTND 130 140 150 160 170 180 IRFVEDNWEN PTLGAWGQGW EVWLNGMEVT QFTYFQQVGG INCNPITTEI TYGLERIAMH 190 200 210 220 230 240 IQNKSNIYDV IWNQDMNNNI ITYGDLFLNN EIEHSSYNFK YADSKLHFDL FEKHLQESNR 250 260 270 280 290 300 IMKLFNNLLF PAYEHLIYSI HYFNLLDAKK KFSTTQRQTH ILNIRNTSKM IATNYYKKQK

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed: 12522265] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bp.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016826 Genomic DNA. Translation: AAO26861.1.
RefSeq	NP_777756.1. NC_004545.1.
3D structure databases
ProteinModelPortal	Q89AV6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000002634; EBBUCP00000002458; EBBUCG00000002634.
GeneID	1058130.
GenomeReviews	Gene locus bbp_127 in contig AE016826_GR.
KEGG	bab:bbp127.
PATRIC	21245033. VBIBucAph80364_0123.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000008062.
HOGENOM	HBG285316.
OMA	CRRPTDG.
ProtClustDB	PRK09348.
Enzyme and pathway databases
BioCyc	BAPH224915:BBP_127-MONOMER.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_BUCBP

Accession

Primary (citable) accession number: Q89AV6

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 15, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program