Reviewed, UniProtKB/Swiss-Prot Q89AS8 (ACKA_BUCBP)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	bbp_164

Organism

Buchnera aphidicola subsp. Baizongia pistaciae [Complete proteome] [HAMAP]

Taxonomic identifier

135842 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	400 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 400	400	Acetate kinase HAMAP MF_00020		PRO_0000107540

Sequences

	Sequence		Length	Mass (Da)
	Q89AS8-1 [UniParc]. Last modified May 30, 2003. Version 1. Checksum: DB7644AE6A79DC1C	FASTA	400	44,388
	10 20 30 40 50 60 MFNKLVLILN CGSSSLKFSV VSSDNYTTKL SGIVEFLNLS QIRFFWKIKK KEYVRVINKS 70 80 90 100 110 120 KSYDYALNYI LTKILKEESK IFNNIACVGH RVVHGGVNLN KSVLITQEII KLITDACSFA 130 140 150 160 170 180 PLHNPINLLG IKASHAVLPH LKEKNVAVFD TSFHSSIPKF AYLYAIPYKF YKKFGIRKYG 190 200 210 220 230 240 AHGISCQYSV CRSSELLQIE LTSLNIIICH LGGGASVSVV KNGVCVDTSM GLTPLEGLIM 250 260 270 280 290 300 GTRSGDIDPS VIFFMNKQLN LSISTINNIL INKSGLLGLS GVSSDFRNLE SEYNSNIRIK 310 320 330 340 350 360 LAIDMFCYRL SKYISGYMSV VKGKLHGIVF TGGIGENSSL VRSIVISKLA FLNFKLNSDI 370 380 390 400 NMLMKSGKEG FINIKNTFPI LVIPANEELI IAKESFSEIN

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed: 12522265] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016826 Genomic DNA. Translation: AAO26897.1.
RefSeq	NP_777792.1.
3D structure databases
HSSP	HSSP built from PDB template 1G99 based on UniProtKB P38502.
ModBase	Search...
Genome annotation databases
GeneID	1058568.
GenomeReviews	Gene locus bbp_164 in contig AE016826_GR.
KEGG	bab:bbp164.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q89AS8.
OMA	Q89AS8. PHLKDKN.
Enzyme and pathway databases
BioCyc	BAPH224915:BBP_164-MON.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate_kin. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_BUCBP

Accession

Primary (citable) accession number: Q89AS8

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2003
Last sequence update:	May 30, 2003
Last modified:	June 16, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)