Q89AS7 (PTA_BUCBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphate acetyltransferase
EC=2.3.1.8

Alternative name(s):
Phosphotransacetylase

Gene names

Name:	pta
Ordered Locus Names:	bbp_165

Organism

Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) [Complete proteome] [HAMAP]

Taxonomic identifier

224915 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	715 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in acetate metabolism By similarity.
Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate.
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.
Subunit structure	Homohexamer By similarity.
Subcellular location	Cytoplasm Potential.
Domain	The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.
Sequence similarities	In the N-terminal section; belongs to the CobB/CobQ family. In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 715	715	Phosphate acetyltransferase		PRO_0000179124
Regions
	Region	392 – 715	324	Phosphate acetyltransferase

Sequences

	Sequence		Length	Mass (Da)
	Q89AS7 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: EC82E2C55C0DAE1C	FASTA	715	80,489
	10 20 30 40 50 60 MTRTIMLVPI GKNIGLTTIS LSVISAMKRC KFNVKFLKSA IEYSNTNYNI DDTSLILKDT 70 80 90 100 110 120 QSLSYINPLI VDFINQFSLK QIKQRIVDYI LSKVYAKKEK YDIFLIEGFD TKSHTYVLSN 130 140 150 160 170 180 DINYYISKSI NVEIVFVCAV DRSSQLDINN IVYIINNVFK KNKNINIRGV IINELCQKVR 190 200 210 220 230 240 NDYGNVNLFD MFKSSVKKIN FGDVKYDFLF QKNGIEVLGC VPWIHKLMEP SVKILCDKYL 250 260 270 280 290 300 GANIIYDRCM NSQYIKTFII YDTNEDIKNA KKFHRSLLII PAISNDKIKE ICVQINKNKI 310 320 330 340 350 360 LISAILLTNF LNVHDKCTDF IDQLKIANCT ICSTPNDVFT VVSLLHKFNF KLDNKNYQLN 370 380 390 400 410 420 IIENDMSRHI NLDWIRSLKH SYQYNSICLP SLFIYNLKHL AKKFMKNILL PEGCELRIIK 430 440 450 460 470 480 AASICSKNDI AYCTLLGNPK KIKNIAESNN IVLNSNIEII DPKLIRKNYV ERLCHLRRHH 490 500 510 520 530 540 GITLAHANEL VKDNSILSTL ILESKKVDGL VSGSIGTTSS IILPALQLIK TSPGSSLISS 550 560 570 580 590 600 VFFMLLSDYV TLYADCAVNI NPDATQLAEI AIQSSNTARL FGIFPKVAML SYATGCSGFG 610 620 630 640 650 660 DTVDKVKEAT RIVQERSPNL IVDGPIQYDA AINRSVAKLK CPHSLVAGNA TVFIFPDLNS 670 680 690 700 710 GNITYKAVQR SANILSIGPI LQGINQPVND LSRGSSVQDI VYTIAVTVLQ SSLSH

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed: 12522265] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bp.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016826 Genomic DNA. Translation: AAO26898.1.
RefSeq	NP_777793.1. NC_004545.1.
3D structure databases
ProteinModelPortal	Q89AS7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000002424; EBBUCP00000002248; EBBUCG00000002424.
GeneID	1058580.
GenomeReviews	Gene locus bbp_165 in contig AE016826_GR.
KEGG	bab:bbp165.
PATRIC	21245107. VBIBucAph80364_0160.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000007729.
HOGENOM	HBG576804.
OMA	ININPTA.
Enzyme and pathway databases
BioCyc	BAPH224915:BBP_165-MONOMER.
Family and domain databases
InterPro	IPR010766. DRTGG. IPR016475. P-Actrans_bac. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
KO	K13788.
Pfam	PF07085. DRTGG. 1 hit. PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF006107. PhpActrans_proteobac. 1 hit.
TIGRFAMs	TIGR00651. Pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTA_BUCBP

Accession

Primary (citable) accession number: Q89AS7

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program