Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q89AS7 (PTA_BUCBP) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:bbp_165
OrganismBuchnera aphidicola subsp. Baizongia pistaciae (strain Bp) [Complete proteome] [HAMAP]
Taxonomic identifier224915 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length715 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in acetate metabolism By similarity.

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subunit structure

Homohexamer By similarity.

Subcellular location

Cytoplasm Potential.

Domain

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.

Sequence similarities

In the N-terminal section; belongs to the CobB/CobQ family.

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 715715Phosphate acetyltransferase
PRO_0000179124

Regions

Region392 – 715324Phosphate acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
Q89AS7 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: EC82E2C55C0DAE1C

FASTA71580,489
        10         20         30         40         50         60 
MTRTIMLVPI GKNIGLTTIS LSVISAMKRC KFNVKFLKSA IEYSNTNYNI DDTSLILKDT 

        70         80         90        100        110        120 
QSLSYINPLI VDFINQFSLK QIKQRIVDYI LSKVYAKKEK YDIFLIEGFD TKSHTYVLSN 

       130        140        150        160        170        180 
DINYYISKSI NVEIVFVCAV DRSSQLDINN IVYIINNVFK KNKNINIRGV IINELCQKVR 

       190        200        210        220        230        240 
NDYGNVNLFD MFKSSVKKIN FGDVKYDFLF QKNGIEVLGC VPWIHKLMEP SVKILCDKYL 

       250        260        270        280        290        300 
GANIIYDRCM NSQYIKTFII YDTNEDIKNA KKFHRSLLII PAISNDKIKE ICVQINKNKI 

       310        320        330        340        350        360 
LISAILLTNF LNVHDKCTDF IDQLKIANCT ICSTPNDVFT VVSLLHKFNF KLDNKNYQLN 

       370        380        390        400        410        420 
IIENDMSRHI NLDWIRSLKH SYQYNSICLP SLFIYNLKHL AKKFMKNILL PEGCELRIIK 

       430        440        450        460        470        480 
AASICSKNDI AYCTLLGNPK KIKNIAESNN IVLNSNIEII DPKLIRKNYV ERLCHLRRHH 

       490        500        510        520        530        540 
GITLAHANEL VKDNSILSTL ILESKKVDGL VSGSIGTTSS IILPALQLIK TSPGSSLISS 

       550        560        570        580        590        600 
VFFMLLSDYV TLYADCAVNI NPDATQLAEI AIQSSNTARL FGIFPKVAML SYATGCSGFG 

       610        620        630        640        650        660 
DTVDKVKEAT RIVQERSPNL IVDGPIQYDA AINRSVAKLK CPHSLVAGNA TVFIFPDLNS 

       670        680        690        700        710 
GNITYKAVQR SANILSIGPI LQGINQPVND LSRGSSVQDI VYTIAVTVLQ SSLSH 

« Hide

References

[1]"Reductive genome evolution in Buchnera aphidicola."
van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.
Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bp.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016826 Genomic DNA. Translation: AAO26898.1.
RefSeqNP_777793.1. NC_004545.1.

3D structure databases

ProteinModelPortalQ89AS7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224915.bbp165.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO26898; AAO26898; bbp_165.
GeneID1058580.
KEGGbab:bbp165.
PATRIC21245107. VBIBucAph80364_0160.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0280.
KOK13788.
OMAYSIANDN.
OrthoDBEOG6BKJ5W.

Enzyme and pathway databases

BioCycBAPH224915:GJ9D-165-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

Gene3D3.40.1390.20. 1 hit.
InterProIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view]
PfamPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTA_BUCBP
AccessionPrimary (citable) accession number: Q89AS7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: June 1, 2003
Last modified: June 11, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways