Reviewed, UniProtKB/Swiss-Prot Q89AK3 (6PGL_BUCBP)

Names and origin

Protein names

Recommended name:
    6-phosphogluconolactonase
      Short name=6-P-gluconolactonase
    EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	bbp_274

Organism

Buchnera aphidicola subsp. Baizongia pistaciae [Complete proteome] [HAMAP]

Taxonomic identifier

135842 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity. HAMAP MF_01605
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	6-phosphogluconolactonase HAMAP MF_01605		PRO_0000171130

Sequences

	Sequence		Length	Mass (Da)
	Q89AK3-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: C65076CFA856C926	FASTA	331	37,872
	10 20 30 40 50 60 MKQIIYITLA KNQEIEVWKL HDDFSLNLLQ RISTQGEPQP IIISKDKKYL YIGVRPKFKV 70 80 90 100 110 120 YSYKIKADGT LTKHACSTLP GSPNHFEIDH TGKYLFSSSY HFNCLSITPL DTLGIPRPVT 130 140 150 160 170 180 QTIKNIFGCH ASKMNCYNTC LFISALKKDC IYAYNFKKNG KLLKNTRKNF MTNVNFGPRH 190 200 210 220 230 240 LDLQKCNNRL YSVNELNGSV DIWSINSFSN ELILLKNINI MSKNYCNAAW SSDLHISPCE 250 260 270 280 290 300 KFLYVSDRIE NTISIIKLEK DVQNIEKIGH IKTELQPRTF SINSTGENLI VVGEKSNSFS 310 320 330 VYKISKITGL LELKNTYSTG NRPVWISSLM L

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed: 12522265] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016826 Genomic DNA. Translation: AAO26999.1.
RefSeq	NP_777894.1.
3D structure databases
SMR	Q89AK3. Positions 1-328.
ModBase	Search...
Genome annotation databases
GeneID	1058415.
GenomeReviews	Gene locus bbp_274 in contig AE016826_GR.
KEGG	bab:bbp274.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG741123.
OMA	AYVINEL.
Enzyme and pathway databases
BioCyc	BAPH224915:BBP_274-MONOMER.
Family and domain databases
HAMAP	MF_01605. 6P-gluconolactonase. [Tree]
InterPro	IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_BUCBP

Accession

Primary (citable) accession number: Q89AK3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2003
Last modified:	February 9, 2010
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)