Q89AK3 (6PGL_BUCBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
6-phosphogluconolactonase
Short name=6-P-gluconolactonase
EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	bbp_274

Organism

Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) [Complete proteome] [HAMAP]

Taxonomic identifier

224915 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity. HAMAP MF_01605
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	6-phosphogluconolactonase HAMAP MF_01605		PRO_0000171130

Sequences

	Sequence		Length	Mass (Da)
	Q89AK3 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: C65076CFA856C926	FASTA	331	37,872
	10 20 30 40 50 60 MKQIIYITLA KNQEIEVWKL HDDFSLNLLQ RISTQGEPQP IIISKDKKYL YIGVRPKFKV 70 80 90 100 110 120 YSYKIKADGT LTKHACSTLP GSPNHFEIDH TGKYLFSSSY HFNCLSITPL DTLGIPRPVT 130 140 150 160 170 180 QTIKNIFGCH ASKMNCYNTC LFISALKKDC IYAYNFKKNG KLLKNTRKNF MTNVNFGPRH 190 200 210 220 230 240 LDLQKCNNRL YSVNELNGSV DIWSINSFSN ELILLKNINI MSKNYCNAAW SSDLHISPCE 250 260 270 280 290 300 KFLYVSDRIE NTISIIKLEK DVQNIEKIGH IKTELQPRTF SINSTGENLI VVGEKSNSFS 310 320 330 VYKISKITGL LELKNTYSTG NRPVWISSLM L

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed: 12522265] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bp.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016826 Genomic DNA. Translation: AAO26999.1.
RefSeq	NP_777894.1. NC_004545.1.
3D structure databases
ProteinModelPortal	Q89AK3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000002642; EBBUCP00000002466; EBBUCG00000002642.
GeneID	1058415.
GenomeReviews	Gene locus bbp_274 in contig AE016826_GR.
KEGG	bab:bbp274.
PATRIC	21245333. VBIBucAph80364_0269.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000007987.
HOGENOM	HBG741123.
OMA	CINELNS.
ProtClustDB	PRK11028.
Enzyme and pathway databases
BioCyc	BAPH224915:BBP_274-MONOMER.
Family and domain databases
HAMAP	MF_01605. 6P-gluconolactonase. [Tree]
InterPro	IPR022528. 6-phosphogluconolactonase_YbhE. IPR019405. Lactonase_7-beta_prop. IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
KO	K07404.
Pfam	PF10282. Lactonase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

6PGL_BUCBP

Accession

Primary (citable) accession number: Q89AK3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program