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Q89AJ7

- ODO1_BUCBP

UniProt

Q89AJ7 - ODO1_BUCBP

Protein

Oxoglutarate dehydrogenase

Gene

sucA

Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (16 Jun 2003)
      Previous versions | rss
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    Functioni

    The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.By similarity

    Catalytic activityi

    2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2.

    Cofactori

    Thiamine pyrophosphate.By similarity

    GO - Molecular functioni

    1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
    2. thiamine pyrophosphate binding Source: InterPro

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Thiamine pyrophosphate

    Enzyme and pathway databases

    BioCyciBAPH224915:GJ9D-280-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Oxoglutarate dehydrogenase (EC:1.2.4.2)
    Gene namesi
    Name:sucA
    Ordered Locus Names:bbp_280
    OrganismiBuchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
    Taxonomic identifieri224915 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000000601: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 916916Oxoglutarate dehydrogenasePRO_0000162189Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Protein-protein interaction databases

    STRINGi224915.bbp280.

    Structurei

    3D structure databases

    ProteinModelPortaliQ89AJ7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0567.
    KOiK00164.
    OMAiQHAPNKE.
    OrthoDBiEOG6V1M1F.

    Family and domain databases

    Gene3Di3.40.50.970. 2 hits.
    InterProiIPR011603. 2oxoglutarate_DH_E1.
    IPR001017. DH_E1.
    IPR029061. THDP-binding.
    IPR005475. Transketolase-like_Pyr-bd.
    [Graphical view]
    PANTHERiPTHR23152. PTHR23152. 1 hit.
    PfamiPF00676. E1_dh. 1 hit.
    PF02779. Transket_pyr. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
    SMARTiSM00861. Transket_pyr. 1 hit.
    [Graphical view]
    SUPFAMiSSF52518. SSF52518. 2 hits.
    TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q89AJ7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYKNEFNSSW MSSFNSSYID NLYNKFLLDP TSIDNSWYIV FTELSKENYI    50
    NSTNKYLNNK FQDSKDTIKL TIELLINIFR TLGYKFAHLN PLDTFKNDNS 100
    LSLKKFLKSS EAFRIQDSYL VKLSQYVLDD ITTKNVYDDY KNIYCKRIGY 150
    QFMHIHNSNE MNWIKNYIET KHSNILKKKK KIQILKHLII SEMLEKYFSS 200
    KFPSIKRFSI EGAESLIPML KEVIKYTKKF NLHKIIFGMS HRGRLNVLAN 250
    ILDKPIKTIF NEFCENNSNN FNSGDVKYHM GFCCTKTIGL RKIILDLKSN 300
    PSHLEVINPV VVGSSRAYID SNDNLNDENI LPIIIHGDAA ISGQGVVQEL 350
    LNMSQARGYK VGGTIHIVVN NQIGFTTSKV KDLRTSQYCT DIAKMIDSPI 400
    FHVNADDPES VIFVTHLALN YRFCFKKDVF INLVCYRRHG HNEIDDPSIT 450
    QPVLYSKIKN HPTTATSYYN KLLLKNIINK SFLITYQKKI KKKLDVEYNL 500
    HNKKMSEKRL KCCSIVKADY INVSNTPINN ISQSDLTILA KKIFSIPNNI 550
    EVHNRVFKIY KDRLKMANNE KLFDWGASEL LAYASLLNEG ISCRLSGEDV 600
    CRGTFFHRHA VIHDQKNDSK YIPLKNIKLK QGNFYIWDSV LSEEATLAFE 650
    YGYSIDQKNT LNVWEAQFGD FANGAQIIID QFICSGEQKW NVTCNLVMLL 700
    PHGYEGQGPE HSSARIERYL QLSANNNIKI IIPTISSQIY HIIRKQAFSL 750
    IKKPLIIMSP KSLLRFPLAA SSLSELSNGK FRTVIDEIDN LDTKKVQRII 800
    LCSGKIYYDL LTQRRINQQK NIVILRIEQI YPRPTKKLSA ILYNYKDVHD 850
    YIWCQEEPCN QGAWLYHKSY LKKLLPKHSK LNYVGRSSSA SPATGYMKIH 900
    KEQQKKIIYD ALNISD 916
    Length:916
    Mass (Da):106,047
    Last modified:June 16, 2003 - v1
    Checksum:i9421601E0BE528CB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016826 Genomic DNA. Translation: AAO27005.1.
    RefSeqiNP_777900.1. NC_004545.1.

    Genome annotation databases

    EnsemblBacteriaiAAO27005; AAO27005; bbp_280.
    GeneIDi1058600.
    KEGGibab:bbp280.
    PATRICi21245347. VBIBucAph80364_0276.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016826 Genomic DNA. Translation: AAO27005.1 .
    RefSeqi NP_777900.1. NC_004545.1.

    3D structure databases

    ProteinModelPortali Q89AJ7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224915.bbp280.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO27005 ; AAO27005 ; bbp_280 .
    GeneIDi 1058600.
    KEGGi bab:bbp280.
    PATRICi 21245347. VBIBucAph80364_0276.

    Phylogenomic databases

    eggNOGi COG0567.
    KOi K00164.
    OMAi QHAPNKE.
    OrthoDBi EOG6V1M1F.

    Enzyme and pathway databases

    BioCyci BAPH224915:GJ9D-280-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.970. 2 hits.
    InterProi IPR011603. 2oxoglutarate_DH_E1.
    IPR001017. DH_E1.
    IPR029061. THDP-binding.
    IPR005475. Transketolase-like_Pyr-bd.
    [Graphical view ]
    PANTHERi PTHR23152. PTHR23152. 1 hit.
    Pfami PF00676. E1_dh. 1 hit.
    PF02779. Transket_pyr. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
    SMARTi SM00861. Transket_pyr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52518. SSF52518. 2 hits.
    TIGRFAMsi TIGR00239. 2oxo_dh_E1. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bp.

    Entry informationi

    Entry nameiODO1_BUCBP
    AccessioniPrimary (citable) accession number: Q89AJ7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2003
    Last sequence update: June 16, 2003
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3