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Reviewed, UniProtKB/Swiss-Prot Q89AJ7 (ODO1_BUCBP)

Last modified June 16, 2009. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Oxoglutarate dehydrogenase
    EC=1.2.4.2
Gene names
Name: sucA
Ordered Locus Names: bbp_280
OrganismBuchnera aphidicola subsp. Baizongia pistaciae [Complete proteome] [HAMAP]
Taxonomic identifier135842 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length916 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.

Catalytic activity

2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2.

Cofactor

Thiamine pyrophosphate By similarity.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the alpha-ketoglutarate dehydrogenase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 916916Oxoglutarate dehydrogenase
PRO_0000162189

Sequences

Sequence LengthMass (Da)Tools
Q89AJ7-1 [UniParc].

Last modified June 16, 2003. Version 1.
Checksum: 9421601E0BE528CB

FASTA916106,047
        10         20         30         40         50         60 
MYKNEFNSSW MSSFNSSYID NLYNKFLLDP TSIDNSWYIV FTELSKENYI NSTNKYLNNK 

        70         80         90        100        110        120 
FQDSKDTIKL TIELLINIFR TLGYKFAHLN PLDTFKNDNS LSLKKFLKSS EAFRIQDSYL 

       130        140        150        160        170        180 
VKLSQYVLDD ITTKNVYDDY KNIYCKRIGY QFMHIHNSNE MNWIKNYIET KHSNILKKKK 

       190        200        210        220        230        240 
KIQILKHLII SEMLEKYFSS KFPSIKRFSI EGAESLIPML KEVIKYTKKF NLHKIIFGMS 

       250        260        270        280        290        300 
HRGRLNVLAN ILDKPIKTIF NEFCENNSNN FNSGDVKYHM GFCCTKTIGL RKIILDLKSN 

       310        320        330        340        350        360 
PSHLEVINPV VVGSSRAYID SNDNLNDENI LPIIIHGDAA ISGQGVVQEL LNMSQARGYK 

       370        380        390        400        410        420 
VGGTIHIVVN NQIGFTTSKV KDLRTSQYCT DIAKMIDSPI FHVNADDPES VIFVTHLALN 

       430        440        450        460        470        480 
YRFCFKKDVF INLVCYRRHG HNEIDDPSIT QPVLYSKIKN HPTTATSYYN KLLLKNIINK 

       490        500        510        520        530        540 
SFLITYQKKI KKKLDVEYNL HNKKMSEKRL KCCSIVKADY INVSNTPINN ISQSDLTILA 

       550        560        570        580        590        600 
KKIFSIPNNI EVHNRVFKIY KDRLKMANNE KLFDWGASEL LAYASLLNEG ISCRLSGEDV 

       610        620        630        640        650        660 
CRGTFFHRHA VIHDQKNDSK YIPLKNIKLK QGNFYIWDSV LSEEATLAFE YGYSIDQKNT 

       670        680        690        700        710        720 
LNVWEAQFGD FANGAQIIID QFICSGEQKW NVTCNLVMLL PHGYEGQGPE HSSARIERYL 

       730        740        750        760        770        780 
QLSANNNIKI IIPTISSQIY HIIRKQAFSL IKKPLIIMSP KSLLRFPLAA SSLSELSNGK 

       790        800        810        820        830        840 
FRTVIDEIDN LDTKKVQRII LCSGKIYYDL LTQRRINQQK NIVILRIEQI YPRPTKKLSA 

       850        860        870        880        890        900 
ILYNYKDVHD YIWCQEEPCN QGAWLYHKSY LKKLLPKHSK LNYVGRSSSA SPATGYMKIH 

       910 
KEQQKKIIYD ALNISD 

« Hide

Cross-references

Sequence databases

AE016826 Genomic DNA. Translation: AAO27005.1.
RefSeqNP_777900.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1058600.
GenomeReviewsGene locus bbp_280 in contig AE016826_GR.
KEGGbab:bbp280.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ89AJ7.
OMAQ89AJ7. FEEFLQI.

Enzyme and pathway databases

BioCycBAPH224915:BBP_280-MON.

Family and domain databases

InterProIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR005475. Transketolase_central-reg.
[Graphical view]
PANTHERPTHR23152. 2oxoglutarate_DH_E1. 1 hit.
PfamPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFPIRSF000157. Oxoglu_dh_E1. 1 hit.
TIGRFAMsTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetSearch...

Entry information

Entry nameODO1_BUCBP
AccessionPrimary (citable) accession number: Q89AJ7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: June 16, 2003
Last modified: June 16, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents