SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q89AJ7

- ODO1_BUCBP

UniProt

Q89AJ7 - ODO1_BUCBP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Oxoglutarate dehydrogenase
Gene
sucA, bbp_280
Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.

Catalytic activityi

2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2.

Cofactori

Thiamine pyrophosphate By similarity.

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Thiamine pyrophosphate

Enzyme and pathway databases

BioCyciBAPH224915:GJ9D-280-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Oxoglutarate dehydrogenase (EC:1.2.4.2)
Gene namesi
Name:sucA
Ordered Locus Names:bbp_280
OrganismiBuchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Taxonomic identifieri224915 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000601: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 916916Oxoglutarate dehydrogenase
PRO_0000162189Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.

Protein-protein interaction databases

STRINGi224915.bbp280.

Structurei

3D structure databases

ProteinModelPortaliQ89AJ7.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0567.
KOiK00164.
OMAiQHAPNKE.
OrthoDBiEOG6V1M1F.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q89AJ7-1 [UniParc]FASTAAdd to Basket

« Hide

MYKNEFNSSW MSSFNSSYID NLYNKFLLDP TSIDNSWYIV FTELSKENYI    50
NSTNKYLNNK FQDSKDTIKL TIELLINIFR TLGYKFAHLN PLDTFKNDNS 100
LSLKKFLKSS EAFRIQDSYL VKLSQYVLDD ITTKNVYDDY KNIYCKRIGY 150
QFMHIHNSNE MNWIKNYIET KHSNILKKKK KIQILKHLII SEMLEKYFSS 200
KFPSIKRFSI EGAESLIPML KEVIKYTKKF NLHKIIFGMS HRGRLNVLAN 250
ILDKPIKTIF NEFCENNSNN FNSGDVKYHM GFCCTKTIGL RKIILDLKSN 300
PSHLEVINPV VVGSSRAYID SNDNLNDENI LPIIIHGDAA ISGQGVVQEL 350
LNMSQARGYK VGGTIHIVVN NQIGFTTSKV KDLRTSQYCT DIAKMIDSPI 400
FHVNADDPES VIFVTHLALN YRFCFKKDVF INLVCYRRHG HNEIDDPSIT 450
QPVLYSKIKN HPTTATSYYN KLLLKNIINK SFLITYQKKI KKKLDVEYNL 500
HNKKMSEKRL KCCSIVKADY INVSNTPINN ISQSDLTILA KKIFSIPNNI 550
EVHNRVFKIY KDRLKMANNE KLFDWGASEL LAYASLLNEG ISCRLSGEDV 600
CRGTFFHRHA VIHDQKNDSK YIPLKNIKLK QGNFYIWDSV LSEEATLAFE 650
YGYSIDQKNT LNVWEAQFGD FANGAQIIID QFICSGEQKW NVTCNLVMLL 700
PHGYEGQGPE HSSARIERYL QLSANNNIKI IIPTISSQIY HIIRKQAFSL 750
IKKPLIIMSP KSLLRFPLAA SSLSELSNGK FRTVIDEIDN LDTKKVQRII 800
LCSGKIYYDL LTQRRINQQK NIVILRIEQI YPRPTKKLSA ILYNYKDVHD 850
YIWCQEEPCN QGAWLYHKSY LKKLLPKHSK LNYVGRSSSA SPATGYMKIH 900
KEQQKKIIYD ALNISD 916
Length:916
Mass (Da):106,047
Last modified:June 16, 2003 - v1
Checksum:i9421601E0BE528CB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016826 Genomic DNA. Translation: AAO27005.1.
RefSeqiNP_777900.1. NC_004545.1.

Genome annotation databases

EnsemblBacteriaiAAO27005; AAO27005; bbp_280.
GeneIDi1058600.
KEGGibab:bbp280.
PATRICi21245347. VBIBucAph80364_0276.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016826 Genomic DNA. Translation: AAO27005.1 .
RefSeqi NP_777900.1. NC_004545.1.

3D structure databases

ProteinModelPortali Q89AJ7.
ModBasei Search...

Protein-protein interaction databases

STRINGi 224915.bbp280.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO27005 ; AAO27005 ; bbp_280 .
GeneIDi 1058600.
KEGGi bab:bbp280.
PATRICi 21245347. VBIBucAph80364_0276.

Phylogenomic databases

eggNOGi COG0567.
KOi K00164.
OMAi QHAPNKE.
OrthoDBi EOG6V1M1F.

Enzyme and pathway databases

BioCyci BAPH224915:GJ9D-280-MONOMER.

Family and domain databases

Gene3Di 3.40.50.970. 2 hits.
InterProi IPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view ]
PANTHERi PTHR23152. PTHR23152. 1 hit.
Pfami PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view ]
PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTi SM00861. Transket_pyr. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 2 hits.
TIGRFAMsi TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bp.

Entry informationi

Entry nameiODO1_BUCBP
AccessioniPrimary (citable) accession number: Q89AJ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: June 16, 2003
Last modified: June 11, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi