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Q89AI7

- G6PD_BUCBP

UniProt

Q89AI7 - G6PD_BUCBP

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Protein
Glucose-6-phosphate 1-dehydrogenase
Gene
zwf, bbp_298
Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone By similarity.UniRule annotation

Catalytic activityi

D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei48 – 481NADP By similarity
Binding sitei145 – 1451NADP By similarity
Binding sitei175 – 1751Substrate By similarity
Binding sitei179 – 1791Substrate By similarity
Binding sitei213 – 2131Substrate By similarity
Binding sitei232 – 2321Substrate By similarity
Active sitei237 – 2371Proton acceptor By similarity
Binding sitei340 – 3401Substrate By similarity
Binding sitei345 – 3451Substrate By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi90 – 912NADP By similarity

GO - Molecular functioni

  1. NADP binding Source: UniProtKB-HAMAP
  2. glucose-6-phosphate dehydrogenase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciBAPH224915:GJ9D-298-MONOMER.
UniPathwayiUPA00115; UER00408.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate 1-dehydrogenase (EC:1.1.1.49)
Short name:
G6PD
Gene namesi
Name:zwf
Ordered Locus Names:bbp_298
OrganismiBuchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Taxonomic identifieri224915 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000601: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 490490Glucose-6-phosphate 1-dehydrogenaseUniRule annotation
PRO_0000068114Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224915.bbp298.

Structurei

3D structure databases

ProteinModelPortaliQ89AI7.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0364.
KOiK00036.
OMAiDSIMEAW.
OrthoDBiEOG61308Z.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00966. G6PD.
InterProiIPR001282. G6P_DH.
IPR019796. G6P_DH_AS.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR23429. PTHR23429. 1 hit.
PfamiPF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000110. G6PD. 1 hit.
PRINTSiPR00079. G6PDHDRGNASE.
TIGRFAMsiTIGR00871. zwf. 1 hit.
PROSITEiPS00069. G6P_DEHYDROGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q89AI7-1 [UniParc]FASTAAdd to Basket

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MKNKNSGYDL VIFGAKGDLS CRKLLPSLYQ LEKKNKLCTH TRIIGVGRAN    50
WDKIIYTNVV YKSLIKFLNE TIIESIWKKF SSRLEFCNLD INCLHNFKKL 100
KQIIQQNNNI IINYLAMPPH TFGNICLGLE SINLNLEPTR IIIEKPLGSS 150
LKTSININNK IGKFFKEKQI FRIDHYLGKE TIQNLLAFRF SNSLFYYNWN 200
NKFIDHVQIT VSETIGVEGR FNYFDTVGQI KDMVQNHLLQ ILTITTMSTP 250
IDCHENSIRD EKVKILKSLR PFNINNIHKN VILGQYTSGI INQKKVKSYL 300
DETNNQEYQM NKYTETFVSM KIYIDNDQWS GVPFYLRTGK RLPKKCSEIV 350
IFFKTPPLNI FSKNYNTLSK NKLILSLQPN EAIKIYILNK KPKLTSQYKL 400
DLITLDFNYS KFYKKIQLSD AYEKLLLESM KGIQSLFVRR DEVELAWKWI 450
DSTLQCLHLK PRLPDLYPAG TWGPARSKTM INNDGYEWNE 490
Length:490
Mass (Da):57,318
Last modified:June 1, 2003 - v1
Checksum:iF5EE7D9055965AD9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016826 Genomic DNA. Translation: AAO27023.1.
RefSeqiNP_777918.1. NC_004545.1.

Genome annotation databases

EnsemblBacteriaiAAO27023; AAO27023; bbp_298.
GeneIDi1058476.
KEGGibab:bbp298.
PATRICi21245383. VBIBucAph80364_0294.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016826 Genomic DNA. Translation: AAO27023.1 .
RefSeqi NP_777918.1. NC_004545.1.

3D structure databases

ProteinModelPortali Q89AI7.
ModBasei Search...

Protein-protein interaction databases

STRINGi 224915.bbp298.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO27023 ; AAO27023 ; bbp_298 .
GeneIDi 1058476.
KEGGi bab:bbp298.
PATRICi 21245383. VBIBucAph80364_0294.

Phylogenomic databases

eggNOGi COG0364.
KOi K00036.
OMAi DSIMEAW.
OrthoDBi EOG61308Z.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00408 .
BioCyci BAPH224915:GJ9D-298-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_00966. G6PD.
InterProi IPR001282. G6P_DH.
IPR019796. G6P_DH_AS.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
PANTHERi PTHR23429. PTHR23429. 1 hit.
Pfami PF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000110. G6PD. 1 hit.
PRINTSi PR00079. G6PDHDRGNASE.
TIGRFAMsi TIGR00871. zwf. 1 hit.
PROSITEi PS00069. G6P_DEHYDROGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bp.

Entry informationi

Entry nameiG6PD_BUCBP
AccessioniPrimary (citable) accession number: Q89AI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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