Reviewed, UniProtKB/Swiss-Prot Q89AI2 (RSMC_BUCBP)

Names and origin

Protein names

Recommended name:
    Ribosomal RNA small subunit methyltransferase C
    EC=2.1.1.52
Alternative name(s):
    rRNA (guanine-N(2)-)-methyltransferase rsmC
    16S rRNA m2G1207 methyltransferase

Gene names

Name:	rsmC
Ordered Locus Names:	bbp_305

Organism

Buchnera aphidicola subsp. Baizongia pistaciae [Complete proteome] [HAMAP]

Taxonomic identifier

135842 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	326 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle By similarity.
Catalytic activity	S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N(2)-methylguanine. HAMAP MF_01862
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmC family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA methylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 326	326	Ribosomal RNA small subunit methyltransferase C HAMAP MF_01862		PRO_0000097489

Sequences

	Sequence		Length	Mass (Da)
	Q89AI2-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: F389256FC6EF6DF5	FASTA	326	37,481
	10 20 30 40 50 60 MSSTKNVLIT GNTINFYMPN RPKLKVKMHT QCFNNFKNNQ KNSMFAIIFD VLVNKKIIQN 70 80 90 100 110 120 SDVIIYIWPN SKLEALFQIN YIISLLSKTQ KIFFLGSNRS GIKCIQNLLK KWIIITKIDS 130 140 150 160 170 180 SNHCILYSGI IVLKPIFLYE NFIKFNKWNN IVVKTIPGVF SYNNIDHGTK LLMSTCTKNL 190 200 210 220 230 240 RWKTVLDIGC GSGVLSTYLA TIFPEIKLTL IDSNIAALES SKLTLTSNNV CGEIFPSNIY 250 260 270 280 290 300 SNVHYQNFDL IISNPPLHVE NKLNFSIIDN IIKNSVKYLS NKGEIRIVTL KNVPCHKSFT 310 320 LYFKKYTILK TSSHYKVYQA NYKDRV

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed: 12522265] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016826 Genomic DNA. Translation: AAO27030.1.
RefSeq	NP_777925.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1058474.
GenomeReviews	Gene locus bbp_305 in contig AE016826_GR.
KEGG	bab:bbp305.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q89AI2.
OMA	Q89AI2. IGENRAG.
Enzyme and pathway databases
BioCyc	BAPH224915:BBP_305-MON.
Family and domain databases
HAMAP	MF_01862. Divergent sequence. [Tree]
InterPro	IPR013675. Mtase_sm_N. IPR007848. Small_mtfrase. [Graphical view]
Pfam	PF05175. MTS. 1 hit. PF08468. MTS_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RSMC_BUCBP

Accession

Primary (citable) accession number: Q89AI2

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 21, 2003
Last sequence update:	June 1, 2003
Last modified:	June 16, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)