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Protein

Malonyl CoA-acyl carrier protein transacylase

Gene

fabD

Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein].

Pathway: fatty acid biosynthesis

This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.
View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei93 – 931By similarity
Active sitei202 – 2021By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciBAPH224915:GJ9D-320-MONOMER.
UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
Malonyl CoA-acyl carrier protein transacylase (EC:2.3.1.39)
Short name:
MCT
Gene namesi
Name:fabD
Ordered Locus Names:bbp_320
OrganismiBuchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Taxonomic identifieri224915 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000601 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 311311Malonyl CoA-acyl carrier protein transacylasePRO_0000194211Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224915.bbp320.

Structurei

3D structure databases

ProteinModelPortaliQ89AH0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FabD family.Curated

Phylogenomic databases

eggNOGiCOG0331.
KOiK00645.
OMAiRRIDKTV.
OrthoDBiEOG6W19KW.

Family and domain databases

Gene3Di3.40.366.10. 2 hits.
InterProiIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
PfamiPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000446. Mct. 1 hit.
SUPFAMiSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.

Sequencei

Sequence statusi: Complete.

Q89AH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKYTLLFPG QNDINRKKIL SPFFSKNKIV QSIFRESSEY IGYDIWKLIQ
60 70 80 90 100
DDPKKKLKNN KYSQLVTLVS SIAIYELWKN KQCTHPNLVI GHSLGEYTAL
110 120 130 140 150
VCSQSLKLSD AIQLIITRYK FMMEAMSKKI GLMTAIIGLN ERTIRKLLKK
160 170 180 190 200
YDYSHEVSIA CINTDNQIVL SGERNSVKHI NLHCKKAGAK NIINLYIHPP
210 220 230 240 250
SHCTLMKKAS KKLLYVLKHT TFKIPIYPVI SSTSLKFQNS EQAIRISLAK
260 270 280 290 300
QIYSTVRWNS IIKYIKKDIF IFLEVSTKSI LTNLNKNIIK KSLSISLNCQ
310
ANFLKALKII L
Length:311
Mass (Da):35,797
Last modified:May 30, 2003 - v1
Checksum:i9E9CD2AEA0C6BC03
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016826 Genomic DNA. Translation: AAO27042.1.
RefSeqiNP_777937.1. NC_004545.1.
WP_011091443.1. NC_004545.1.

Genome annotation databases

EnsemblBacteriaiAAO27042; AAO27042; bbp_320.
KEGGibab:bbp320.
PATRICi21245429. VBIBucAph80364_0314.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016826 Genomic DNA. Translation: AAO27042.1.
RefSeqiNP_777937.1. NC_004545.1.
WP_011091443.1. NC_004545.1.

3D structure databases

ProteinModelPortaliQ89AH0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224915.bbp320.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO27042; AAO27042; bbp_320.
KEGGibab:bbp320.
PATRICi21245429. VBIBucAph80364_0314.

Phylogenomic databases

eggNOGiCOG0331.
KOiK00645.
OMAiRRIDKTV.
OrthoDBiEOG6W19KW.

Enzyme and pathway databases

UniPathwayiUPA00094.
BioCyciBAPH224915:GJ9D-320-MONOMER.

Family and domain databases

Gene3Di3.40.366.10. 2 hits.
InterProiIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
PfamiPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000446. Mct. 1 hit.
SUPFAMiSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bp.

Entry informationi

Entry nameiFABD_BUCBP
AccessioniPrimary (citable) accession number: Q89AH0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2003
Last sequence update: May 30, 2003
Last modified: April 29, 2015
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.