Q89AA5 (CYOC_BUCBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome o ubiquinol oxidase subunit 3
EC=1.10.3.-

Alternative name(s):
Cytochrome o ubiquinol oxidase subunit III

Gene names

Name:	cyoC
Ordered Locus Names:	bbp_415

Organism

Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) [Complete proteome] [HAMAP]

Taxonomic identifier

224915 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Baizongia pistaciae)

Protein attributes

Sequence length	194 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration By similarity.
Catalytic activity	Ubiquinol-8 + O2 = Ubiquinone-8 + H2O.
Subcellular location	Cell membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
Biological process	Electron transport Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	aerobic electron transport chain Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	cytochrome o ubiquinol oxidase activity Inferred from electronic annotation. Source: InterPro cytochrome-c oxidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 194	194	Cytochrome o ubiquinol oxidase subunit 3		PRO_0000183898
Regions
	Topological domain	1 – 18	18	Cytoplasmic Potential
	Transmembrane	19 – 41	23	Helical; Potential
	Topological domain	42 – 55	14	Extracellular Potential
	Transmembrane	56 – 78	23	Helical; Potential
	Topological domain	79 – 84	6	Cytoplasmic Potential
	Transmembrane	85 – 107	23	Helical; Potential
	Topological domain	108 – 126	19	Extracellular Potential
	Transmembrane	127 – 149	23	Helical; Potential
	Topological domain	150 – 169	20	Cytoplasmic Potential
	Transmembrane	170 – 192	23	Helical; Potential
	Topological domain	193 – 194	2	Extracellular Potential

Sequences

	Sequence		Length	Mass (Da)
	Q89AA5 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 5100E603AA6CBB02	FASTA	194	22,941
	10 20 30 40 50 60 MKKKYKIDTN IFSKELLGFW LYLMSDCIIF CTLFSVYFIL VDNVAQGPSG HNIFQNNLII 70 80 90 100 110 120 IETFLLLFSS FSCNLVLFEM KNKNLYMVFL WLGITFLLGL LFVFLELFEF FHLINLGFGP 130 140 150 160 170 180 TRSGFLSSFF VLIATHGIHV ISGLIWIIVM IKYVYTFNIT NLIYYRMLCL NLFWHFLDIV 190 WVFIFSFVYL FGMV

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bp.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016826 Genomic DNA. Translation: AAO27125.1.
RefSeq	NP_778020.1. NC_004545.1.
3D structure databases
ProteinModelPortal	Q89AA5.
ModBase	Search...
Protein-protein interaction databases
STRING	224915.bbp415.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAO27125; AAO27125; bbp_415.
GeneID	1058631.
KEGG	bab:bbp415.
PATRIC	21245647. VBIBucAph80364_0416.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1845.
KO	K02299.
OMA	MAIMMFQ.
Enzyme and pathway databases
BioCyc	BAPH224915:GJ9D-415-MONOMER.
Family and domain databases
Gene3D	1.20.120.80. 1 hit.
InterPro	IPR024791. Cyt_c/ubiquinol_Oxase_su3. IPR000298. Cyt_c_oxidase_su3. IPR013833. Cyt_c_oxidase_su3_a-hlx. IPR014206. Cyt_c_ubiqinol_oxidase_su3. [Graphical view]
PANTHER	PTHR11403. PTHR11403. 1 hit.
Pfam	PF00510. COX3. 1 hit. [Graphical view]
SUPFAM	SSF81452. CytC_oxdse_III. 1 hit.
TIGRFAMs	TIGR02842. CyoC. 1 hit.
PROSITE	PS50253. COX3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYOC_BUCBP

Accession

Primary (citable) accession number: Q89AA5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2003
Last modified:	May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program