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Protein

Multidrug resistance-like ATP-binding protein MdlB

Gene

mdlB

Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O + xenobiotic(In) = ADP + phosphate + xenobiotic(Out).

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi373 – 380ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
Biological processTransport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Multidrug resistance-like ATP-binding protein MdlB (EC:3.6.3.44)
Gene namesi
Name:mdlB
Ordered Locus Names:bbp_424
OrganismiBuchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Taxonomic identifieri224915 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000000601 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 46HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei59 – 79HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei143 – 163HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei166 – 186HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei196 – 216HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei260 – 280HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000925011 – 578Multidrug resistance-like ATP-binding protein MdlBAdd BLAST578

Interactioni

Protein-protein interaction databases

STRINGi224915.bbp424.

Structurei

3D structure databases

ProteinModelPortaliQ89A96.
SMRiQ89A96.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 308ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST284
Domaini339 – 573ABC transporterPROSITE-ProRule annotationAdd BLAST235

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105BZ1. Bacteria.
COG1132. LUCA.
KOiK18890.
OMAiVFITQRL.
OrthoDBiPOG091H00DB.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q89A96-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNVIDFWPT LKRLLYYGTN VKKYLILGFT LLLFSSIFEV LNPILISCFI
60 70 80 90 100
KHYFINNTVN YSLKIITYYL ILQILAAILN YHQNIIFNKI SLTVIQKLRY
110 120 130 140 150
DVMSSTLQLP IKMFDQRPIG QFISRITNDT ETIKELYDTV IKSLFQNIIL
160 170 180 190 200
ILITLITMFI LEWRMACIAS IIFPIALIIM LLYQYFSKPI LRKIKVYIAN
210 220 230 240 250
IYNIFNEIIN GIDVIQQFHQ EQKFRKSIKK ISISHYYFRM KILKLDSFLL
260 270 280 290 300
RPLLNFCSTL ILCGLILIFG IYPIGFFEIG TLYAFITYLN RLNEPLITIT
310 320 330 340 350
SQQSIFQQAI VAGERIFEII HTPKQQYGDD SLHFREGNIK VKNLYFSYTN
360 370 380 390 400
NNVYVLKNIN IFIPSKQFIA FVGRTGSGKS TLSKLLIGHY PATLGKICLD
410 420 430 440 450
ERNIQTFTHN VLKKNISIVQ QDPIILNDTI LENITLGRNI STKKVLKILK
460 470 480 490 500
TIKLIQFVNS LPKGLKTLLG ENGNILSIGQ KQLLSIARTL ISCPKILILD
510 520 530 540 550
EATSNVDLDT ENNIKKILSS VKHLTTIIAI THRLSTIKHA DNIFVFNNGE
560 570
IVESGTHYNL IRKKSYYKNM YYSQAIKN
Length:578
Mass (Da):66,827
Last modified:May 30, 2003 - v1
Checksum:i3B84848CE196ADF7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016826 Genomic DNA. Translation: AAO27134.1.
RefSeqiWP_011091535.1. NC_004545.1.

Genome annotation databases

EnsemblBacteriaiAAO27134; AAO27134; bbp_424.
KEGGibab:bbp_424.

Similar proteinsi

Entry informationi

Entry nameiMDLB_BUCBP
AccessioniPrimary (citable) accession number: Q89A96
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2003
Last sequence update: May 30, 2003
Last modified: June 7, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families