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Q89A46

- TRMB_BUCBP

UniProt

Q89A46 - TRMB_BUCBP

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Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, bbp_499
Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei66 – 661S-adenosyl-L-methionine By similarity
Binding sitei91 – 911S-adenosyl-L-methionine By similarity
Binding sitei118 – 1181S-adenosyl-L-methionine By similarity
Active sitei141 – 1411 By similarity
Binding sitei141 – 1411S-adenosyl-L-methionine By similarity
Binding sitei145 – 1451Substrate By similarity
Binding sitei177 – 1771Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciBAPH224915:GJ9D-499-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:bbp_499
OrganismiBuchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Taxonomic identifieri224915 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000601: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 242242tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
PRO_0000171309Add
BLAST

Proteomic databases

PRIDEiQ89A46.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi224915.bbp499.

Structurei

3D structure databases

ProteinModelPortaliQ89A46.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni214 – 2174Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
KOiK03439.
OMAiHSTLEMA.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q89A46-1 [UniParc]FASTAAdd to Basket

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MYFYLKYNIN NMIMRRVRSF VSRNRKLTQN KRQFLKNYLL KYGIDFSCSY    50
VNFNFIFNNE YPVILEIGFG TGEFLINMAR KNLFSNFLGI EVYIPSILSC 100
LRYIHKYNLP NVKVIFYDAV EVISYMISNN SLSEVYILFP DPWPKRRHHK 150
RRIITKELLE VILKKLVFGG YLNIATDCQI YAKSILNIIE NIKGYINLSN 200
TGDYVIRSDY RLVTKFEKKG LVLGNKIFNL KFKSIFNNSN FL 242
Length:242
Mass (Da):28,732
Last modified:June 16, 2003 - v1
Checksum:i9AAF0C3D4D2879A0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016826 Genomic DNA. Translation: AAO27204.1.
RefSeqiNP_778099.1. NC_004545.1.

Genome annotation databases

EnsemblBacteriaiAAO27204; AAO27204; bbp_499.
GeneIDi1058500.
KEGGibab:bbp499.
PATRICi21245815. VBIBucAph80364_0495.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016826 Genomic DNA. Translation: AAO27204.1 .
RefSeqi NP_778099.1. NC_004545.1.

3D structure databases

ProteinModelPortali Q89A46.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224915.bbp499.

Proteomic databases

PRIDEi Q89A46.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO27204 ; AAO27204 ; bbp_499 .
GeneIDi 1058500.
KEGGi bab:bbp499.
PATRICi 21245815. VBIBucAph80364_0495.

Phylogenomic databases

eggNOGi COG0220.
KOi K03439.
OMAi HSTLEMA.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci BAPH224915:GJ9D-499-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bp.

Entry informationi

Entry nameiTRMB_BUCBP
AccessioniPrimary (citable) accession number: Q89A46
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: June 16, 2003
Last modified: June 11, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3