Q89A28 (FENR_BUCBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase
Short name=FNR
EC=1.18.1.2

Alternative name(s):
Flavodoxin reductase
Short name=FLDR
Short name=FLXR

Gene names

Name:	fpr
Ordered Locus Names:	bbp_527

Organism

Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) [Complete proteome] [HAMAP]

Taxonomic identifier

224915 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	249 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transports electrons between flavodoxin or ferredoxin and NADPH By similarity.
Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH.
Cofactor	FAD By similarity.
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 1 family. Contains 1 FAD-binding FR-type domain.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 249	249	Ferredoxin--NADP reductase		PRO_0000167642
Regions
	Domain	2 – 102	101	FAD-binding FR-type
	Nucleotide binding	51 – 54	4	FAD By similarity
	Nucleotide binding	74 – 77	4	FAD By similarity
	Nucleotide binding	144 – 145	2	NADP By similarity
	Nucleotide binding	174 – 175	2	NADP By similarity
	Nucleotide binding	214 – 215	2	NADP By similarity
Sites
	Binding site	54	1	NADP By similarity
	Binding site	117	1	FAD By similarity
	Binding site	117	1	NADP; via amide nitrogen By similarity
	Binding site	246	1	NADP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q89A28 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 16E351770724413B	FASTA	249	29,335
	10 20 30 40 50 60 MNTWITAKII KIKKWKNNLF SVIVNAPISP FTAGQFTKLG YQKKNGKIIQ RAYSFVNAPH 70 80 90 100 110 120 EKNLEFYMVL IKNGQLTTKL YNLNNTDHIQ IKKKSYGFFT LNEIPTCKIL WMFATGTGIG 130 140 150 160 170 180 PYLSMLKYQK NTEKFQKIVL IHAVRYRHDL TYFNEINNLK NIYNKKLYTQ FIISREKTNF 190 200 210 220 230 240 SLSGRIPQLL KTEELEKHIN LFIENNTSHV MLCGNPDMVK QTQNFLINNK NMKKHLRRKP GQISSENYW

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed: 12522265] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bp.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016826 Genomic DNA. Translation: AAO27229.1.
RefSeq	NP_778124.1. NC_004545.1.
3D structure databases
ProteinModelPortal	Q89A28.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000002519; EBBUCP00000002343; EBBUCG00000002519.
GeneID	1058457.
GenomeReviews	Gene locus bbp_527 in contig AE016826_GR.
KEGG	bab:bbp527.
PATRIC	21245877. VBIBucAph80364_0523.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000008152.
HOGENOM	HBG289143.
OMA	FFVLEEV.
PhylomeDB	Q89A28.
Enzyme and pathway databases
BioCyc	BAPH224915:BBP_527-MONOMER.
Family and domain databases
InterPro	IPR017927. Fd_Rdtase_FAD-bd. IPR008333. OxRdtase_FAD-bd_dom. IPR001433. OxRdtase_FAD/NAD-bd. IPR017938. Riboflavin_synthase-like_b-brl. [Graphical view]
KO	K00528.
Pfam	PF00970. FAD_binding_6. 1 hit. PF00175. NAD_binding_1. 1 hit. [Graphical view]
SUPFAM	SSF63380. Riboflavin_synthase_like_b-brl. 1 hit.
PROSITE	PS51384. FAD_FR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FENR_BUCBP

Accession

Primary (citable) accession number: Q89A28

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program