Reviewed, UniProtKB/Swiss-Prot Q89A27 (SYK3_BUCBP)

Names and origin

Protein names

Recommended name:
    Putative lysyl-tRNA synthetase
    EC=6.1.1.6
Alternative name(s):
    Lysine--tRNA ligase
      Short name=LysRS
    GX

Gene names

Name:	poxA
Ordered Locus Names:	bbp_528

Organism

Buchnera aphidicola subsp. Baizongia pistaciae [Complete proteome] [HAMAP]

Taxonomic identifier

135842 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	322 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Could be a lysyl-tRNA synthetase. HAMAP MF_00174
Catalytic activity	ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP MF_00174
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 322	322	Putative lysyl-tRNA synthetase HAMAP MF_00174		PRO_0000152718

Sequences

	Sequence		Length	Mass (Da)
	Q89A27-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 51D38D81A7940511	FASTA	322	37,911
	10 20 30 40 50 60 MNCNYLWKSS ALLKNLHRRA KIIFEIRNYF FNLGILEVET PILSNYSVTD VNFIPFKTKL 70 80 90 100 110 120 QITKKRMWLV PSPEYHMKRL LVQNIGAIYQ ISRSFRNNEF GGPYHNPEFT MLEWYSPYCN 130 140 150 160 170 180 MFDFMKKVEK FLVFCLKVVQ VKYISYQRAF IKYLNIDPLL AKKRELLDLI NKFKFNHLIS 190 200 210 220 230 240 DCDSISTLLE ILFTLKIEPN LNNKKLIFVY HYPADQAILA AINDNDSRVS DRFEVFFKGV 250 260 270 280 290 300 ELGNGFYELT DQAEHIRRFK LNNIQRRHKG ICSVEVDQFF LKSLSRGLPP CSGIAIGLDR 310 320 LIMLSLNLKT INEVIAFPIE RC

References

[1]

"Reductive genome evolution in Buchnera aphidicola." van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003) [PubMed: 12522265] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016826 Genomic DNA. Translation: AAO27230.1.
RefSeq	NP_778125.1.
3D structure databases
HSSP	HSSP built from PDB template 1BBW based on UniProtKB P13030.
ModBase	Search...
Genome annotation databases
GeneID	1058175.
GenomeReviews	Gene locus bbp_528 in contig AE016826_GR.
KEGG	bab:bbp528.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q89A27.
OMA	VFRNEEA.
Enzyme and pathway databases
BioCyc	BAPH224915:BBP_528-MON.
Family and domain databases
HAMAP	MF_00174. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. [Graphical view]
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. [Graphical view]
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYK3_BUCBP

Accession

Primary (citable) accession number: Q89A27

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2003
Last modified:	November 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)