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Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene

mnmG

Organism
Clostridium tetani (strain Massachusetts / E88)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.UniRule annotation

Cofactori

FADUniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi14 – 19FADUniRule annotation6
Nucleotide bindingi273 – 287NADUniRule annotationAdd BLAST15

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processtRNA processing
LigandFAD, Flavoprotein, NAD

Enzyme and pathway databases

BioCyciCTET212717:G1G04-61-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein AUniRule annotation
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotation
Ordered Locus Names:CTC_00099
OrganismiClostridium tetani (strain Massachusetts / E88)
Taxonomic identifieri212717 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001170891 – 623tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGAdd BLAST623

Proteomic databases

PRIDEiQ899S1

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.UniRule annotation

Protein-protein interaction databases

STRINGi212717.CTC00099

Structurei

3D structure databases

ProteinModelPortaliQ899S1
SMRiQ899S1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RE5 Bacteria
COG0445 LUCA
KOiK03495
OMAiFRPGYAI
OrthoDBiPOG091H01O0

Family and domain databases

Gene3Di3.50.50.60, 2 hits
HAMAPiMF_00129 MnmG_GidA, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR026904 GidA-assoc_3
IPR004416 MnmG
IPR002218 MnmG-rel
IPR020595 MnmG-rel_CS
PANTHERiPTHR11806 PTHR11806, 1 hit
PTHR11806:SF0 PTHR11806:SF0, 1 hit
PfamiView protein in Pfam
PF01134 GIDA, 1 hit
PF13932 GIDA_assoc, 1 hit
SUPFAMiSSF51905 SSF51905, 2 hits
TIGRFAMsiTIGR00136 gidA, 1 hit
PROSITEiView protein in PROSITE
PS01280 GIDA_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q899S1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYYAGDYDV VVVGAGHAGC EAALAAARIG CKVLICTISL DSVALMPCNP
60 70 80 90 100
NIGGTAKGHL VREIDALGGE MGVNIDNTFI QSRMLNTSKG PAVHSLRAQA
110 120 130 140 150
DKSRYSNRMK YILENEENVT LKQIEVISID IENGKVKGIL TKNGAYYNAK
160 170 180 190 200
TVVLATGTYL NARIIIGEVA YSGGPNGLFP AKELTKNLMD LGISIRRFKT
210 220 230 240 250
GTPARVNKKT IDFSKMIEQP GDEKIVPFSF LTDKLEREQV SCYLTYTNEN
260 270 280 290 300
THEVIRKNLH RSPMFNGSIE GVGARYCPSI EDKVNRFPDK NKHQVFIEPE
310 320 330 340 350
GEYTNEMYVS GLSSSLPEEI QVAMYRTVPG LENVEFLRTA YAIEYDCIDP
360 370 380 390 400
QELKLSLESK NIEGLFSGGQ INGSSGYEEA AAQGLIAGIN AAMKVKEKDP
410 420 430 440 450
LLLTRSDGYI GVLIDDLVTK GTNEPYRMMT SRSEYRLLLR QGNADLRLTQ
460 470 480 490 500
KGYDVGLVSE ERYKRYINRR ESIKSEIERI KNVQITNKKE VNEFLLSLNS
510 520 530 540 550
SELKKPISLY ELIKRPELDY YKVEQLDKGR INLPEDVQEE VNTTAKYEGY
560 570 580 590 600
IEKQLEQVNQ FKKFENKLLP NDIDYSKVYG LRIESVQKLS KIRPMNIGQA
610 620
SRISGVSPAD ISVLLIYLEH KYK
Length:623
Mass (Da):69,943
Last modified:June 1, 2003 - v1
Checksum:iC9F03133AFAD667C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015927 Genomic DNA Translation: AAO34751.1
RefSeqiWP_011098423.1, NC_004557.1

Genome annotation databases

EnsemblBacteriaiAAO34751; AAO34751; CTC_00099
GeneIDi24253137
KEGGictc:CTC_00099

Similar proteinsi

Entry informationi

Entry nameiMNMG_CLOTE
AccessioniPrimary (citable) accession number: Q899S1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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