Q899J5 (COMB_CLOTE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	CTC_00180

Organism

Clostridium tetani [Complete proteome] [HAMAP]

Taxonomic identifier

1513 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	233 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.
Sequence caution	The sequence AAO34831.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 233	233	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081467

Sequences

	Sequence		Length	Mass (Da)
	Q899J5 [UniParc]. Last modified June 27, 2003. Version 2. Checksum: 4E9D06D95CC57DCE	FASTA	233	25,990
	10 20 30 40 50 60 MNIDIIISAD DIKEEKIKDK SIVVIDILRA TSVIITALNN GCKEVVPVVE IEEALEKVKN 70 80 90 100 110 120 NRKNYILGGE RKALKIEGFD CSNSPLEYKS ELVKGKTLVI TTSNGTRAIK EALLAKDILI 130 140 150 160 170 180 GALINGKAVA EKLISLKNDV VIINAGTYGE FSIDDFICSG YIIDCIAKDM EVKLSDISKV 190 200 210 220 230 AKYLYNMNTN MEFIKEAKHF KRIMELGLFM DLEYCCKKDI VSIVPQYKNG IIK

References

[1]

"The genome sequence of Clostridium tetani, the causative agent of tetanus disease." Brueggemann H., Baeumer S., Fricke W.F., Wiezer A., Liesegang H., Decker I., Herzberg C., Martinez-Arias R., Merkl R., Henne A., Gottschalk G. Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003) [PubMed: 12552129] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Massachusetts / E88.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015927 Genomic DNA. Translation: AAO34831.1. Different initiation.
RefSeq	NP_780894.1. NC_004557.1.
3D structure databases
ProteinModelPortal	Q899J5.
SMR	Q899J5. Positions 1-232.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1059242.
GenomeReviews	Gene locus CTC_00180 in contig AE015927_GR.
KEGG	ctc:CTC00180.
NMPDR	fig|212717.1.peg.116.
PATRIC	19508130. VBICloTet101274_0137.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG633644.
OMA	DFICSGY.
PhylomeDB	Q899J5.
ProtClustDB	PRK00886.
Enzyme and pathway databases
BioCyc	CTET212717:CTC_00180-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_CLOTE

Accession

Primary (citable) accession number: Q899J5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2003
Last sequence update:	June 27, 2003
Last modified:	January 25, 2012
This is version 46 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program