ID   Q899H6_CLOTE            Unreviewed;       798 AA.
AC   Q899H6;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 106.
DE   SubName: Full=Stage II sporulation protein E {ECO:0000313|EMBL:AAO34850.1};
DE            EC=3.1.3.16 {ECO:0000313|EMBL:AAO34850.1};
GN   OrderedLocusNames=CTC_00201 {ECO:0000313|EMBL:AAO34850.1};
OS   Clostridium tetani (strain Massachusetts / E88).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=212717 {ECO:0000313|EMBL:AAO34850.1, ECO:0000313|Proteomes:UP000001412};
RN   [1] {ECO:0000313|EMBL:AAO34850.1, ECO:0000313|Proteomes:UP000001412}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Massachusetts / E88 {ECO:0000313|Proteomes:UP000001412};
RX   PubMed=12552129; DOI=10.1073/pnas.0335853100;
RA   Brueggemann H., Baumer S., Fricke W.F., Wiezer A., Liesegang H., Decker I.,
RA   Herzberg C., Martinez-Arias R., Merkl R., Henne A., Gottschalk G.;
RT   "The genome sequence of Clostridium tetani, the causative agent of tetanus
RT   disease.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE015927; AAO34850.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q899H6; -.
DR   STRING; 212717.CTC_00201; -.
DR   KEGG; ctc:CTC_00201; -.
DR   HOGENOM; CLU_017349_1_0_9; -.
DR   Proteomes; UP000001412; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR014221; SpoII_E.
DR   InterPro; IPR045768; SpoIIE_N.
DR   NCBIfam; TIGR02865; spore_II_E; 1.
DR   PANTHER; PTHR43156:SF12; STAGE II SPORULATION PROTEIN E; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   Pfam; PF19732; SpoIIE_N; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AAO34850.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001412};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        37..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        146..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        188..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        215..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        251..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        274..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          581..794
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   798 AA;  90250 MW;  F824CCD93DA9F221 CRC64;
     MIKMQYGIDI LPYERIKRRD EEGKSSKNIL IKELIKLIVY FLASFLISRV VMVNLMAPFG
     IAFLISNMLE EENSIKLTSA LGTIVGYISI HSSVKDIWMY LILVPLIILN SYILRNKKEK
     SIIKSVFILV FLEVTIYNRF KLHISPLMSI TNSIFQTSCV FSLYYIINYS KICAKGFKTK
     HLFNSEEIIS MCITLSLIIS GVRGLNIFGL SIRNIIALSI IVMIGYIKGS SVGGACGVAM
     GVIIGISTND MTTFVGVFGI CGLISGIFKE SGKVISGLSY VVAFAILKLY SDIGIQFEFR
     EVLLGGSIFL LIPNKIYKKI ETDLDWEMKS ENIKDDYISK VKDIVQEKLT EFSQLLLYMG
     DTLENLAENH NLQMKKKSSS IVEKLADRVC SGCNMKHMCW KREGFYTYSA FSELINNFEN
     KKKVIPNEIE RKCIKRSVLV KNAEEIIKNY IIDEMWKKRI NEYRNFLAEQ ITNISYSVEE
     LTENINSQVH FNKYLENDIR RILNKNKIKY QDIFAYNDKL GKIIVKIHLS PCGGKQKCIK
     EILPFINKVT GKIMCISDDC CNIDSNNERC EITLEESPKY HVATHAGAVC KDGETYSGDS
     YTYGKLKDGK YITVISDGMG SGPEAGQESN AAVNLIEKFA KIGFDRINAI NMVNSLMTIN
     FSENEKFSTV DLSDINLYTG EVDFMKVGAV PSFIKSNGKV EVISSKTLPI GVLDKVDVDL
     VKKDIDNGDI IVMLSDGVLD YDDTEIGKVD WIVKYLEETN MNKPEDICKD IMEKAKLLRK
     GKVKDDMTVV VSKVYSLY
//