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Protein

Protein VP2

Gene

ORF2

Organism
Rabbit hemorrhagic disease virus (strain AST89) (Ra/LV/RHDV/AST89/1989/SP) (RHDV-AST89)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Minor structural protein present in one or two copies per virion. Does not seem to play a role in capsid assembly, but is essential for production of infectious virus (By similarity).By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Protein VP2
Alternative name(s):
Minor capsid protein
Gene namesi
ORF Names:ORF2
OrganismiRabbit hemorrhagic disease virus (strain AST89) (Ra/LV/RHDV/AST89/1989/SP) (RHDV-AST89)
Taxonomic identifieri314538 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageCaliciviridaeLagovirus
Virus hostiOryctolagus cuniculus (Rabbit) [TaxID: 9986]
ProteomesiUP000008653 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Host cytoplasm, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 117117Protein VP2PRO_0000342117Add
BLAST

Interactioni

Subunit structurei

May interact with capsid protein.By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the lagovirus VP2 protein family.Curated

Family and domain databases

InterProiIPR008558. Lagovirus_RHDV_Vp2.
[Graphical view]
PfamiPF05801. DUF840. 1 hit.
[Graphical view]
ProDomiPD009258. DUF840_lagovir. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Q89924-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFLMSEFIG LGLAGASVLS NALLRRQELQ LQRQALENGL VLKADQLGRL
60 70 80 90 100
GFNPNEVKNV IVGNSFSSNV RLSNMHNDAS VVNAYNVYNP ASNGIRKKIK
110
SLNNSVKIYN TTGESSV
Length:117
Mass (Da):12,710
Last modified:November 1, 1996 - v1
Checksum:iDF850317B5CC2CC9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49271 Genomic RNA. Translation: CAA89266.1.
PIRiS46945.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49271 Genomic RNA. Translation: CAA89266.1.
PIRiS46945.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR008558. Lagovirus_RHDV_Vp2.
[Graphical view]
PfamiPF05801. DUF840. 1 hit.
[Graphical view]
ProDomiPD009258. DUF840_lagovir. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

  1. "Molecular cloning, sequence and expression of the capsid protein gene from rabbit hemorrhagic disease virus (Spanish isolate AST/89)."
    Boga J.A., Casais R., Marin M.S., Martin-Alonso J.M., Carmenes R., Prieto M., Parra F.
    J. Gen. Virol. 75:2409-2413(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiVP2_RHDVA
AccessioniPrimary (citable) accession number: Q89924
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: November 1, 1996
Last modified: June 24, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

Translated by a ribosomal terminaition-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.