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Q898A3

- GLSA_CLOTE

UniProt

Q898A3 - GLSA_CLOTE

Protein

Glutaminase

Gene

glsA

Organism
Clostridium tetani (strain Massachusetts / E88)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei62 – 621SubstrateUniRule annotation
    Binding sitei114 – 1141SubstrateUniRule annotation
    Binding sitei159 – 1591SubstrateUniRule annotation
    Binding sitei166 – 1661SubstrateUniRule annotation
    Binding sitei190 – 1901SubstrateUniRule annotation
    Binding sitei242 – 2421SubstrateUniRule annotation
    Binding sitei260 – 2601Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciCTET212717:GJAM-509-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:glsAUniRule annotation
    Ordered Locus Names:CTC_00566
    OrganismiClostridium tetani (strain Massachusetts / E88)
    Taxonomic identifieri212717 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000001412: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 306306GlutaminasePRO_0000110604Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi212717.CTC00566.

    Structurei

    3D structure databases

    ProteinModelPortaliQ898A3.
    SMRiQ898A3. Positions 2-306.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2066.
    KOiK01425.
    OMAiMMDVSQI.
    OrthoDBiEOG6N94BK.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q898A3-1 [UniParc]FASTAAdd to Basket

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    MMQSKIESII EECRKYTREG EVASYIPELK KADKDALGIY IDKLDGNEFC    50
    AGDYDTKFTI QSISKIIALI IAIMDNGMEK VLSKVGVEPS AYSFNSIVTL 100
    EVKNANKPLN PMINAGAIAT VSLIKGNSPE EIIERILEFT RKVTGNKNIK 150
    VNEEVYQSEK KTGDRNRSLA YFMKGTGIIE KDVEKVLDAY FQQCSIEVTC 200
    KDIAKIASFL ANDGVLPSTG ERIIPAEVAK IVKAVMVTCG MYDASGSFAV 250
    KVGIPSKSGV GGGILATVPG VMGIGVFGPA LDKKGNSIAG VKILERLSEE 300
    LNLSIF 306
    Length:306
    Mass (Da):33,064
    Last modified:June 1, 2003 - v1
    Checksum:iE63A047DC52F349B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015927 Genomic DNA. Translation: AAO35183.1.
    RefSeqiNP_781246.1. NC_004557.1.

    Genome annotation databases

    EnsemblBacteriaiAAO35183; AAO35183; CTC_00566.
    GeneIDi1060847.
    KEGGictc:CTC00566.
    PATRICi19508958. VBICloTet101274_0529.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015927 Genomic DNA. Translation: AAO35183.1 .
    RefSeqi NP_781246.1. NC_004557.1.

    3D structure databases

    ProteinModelPortali Q898A3.
    SMRi Q898A3. Positions 2-306.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 212717.CTC00566.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO35183 ; AAO35183 ; CTC_00566 .
    GeneIDi 1060847.
    KEGGi ctc:CTC00566.
    PATRICi 19508958. VBICloTet101274_0529.

    Phylogenomic databases

    eggNOGi COG2066.
    KOi K01425.
    OMAi MMDVSQI.
    OrthoDBi EOG6N94BK.

    Enzyme and pathway databases

    BioCyci CTET212717:GJAM-509-MONOMER.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Massachusetts / E88.

    Entry informationi

    Entry nameiGLSA_CLOTE
    AccessioniPrimary (citable) accession number: Q898A3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 24, 2004
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3