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Q898A3 (GLSA_CLOTE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:CTC_00566
OrganismClostridium tetani (strain Massachusetts / E88) [Complete proteome] [HAMAP]
Taxonomic identifier212717 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 306306Glutaminase HAMAP-Rule MF_00313
PRO_0000110604

Sites

Binding site621Substrate By similarity
Binding site1141Substrate By similarity
Binding site1591Substrate By similarity
Binding site1661Substrate By similarity
Binding site1901Substrate By similarity
Binding site2421Substrate By similarity
Binding site2601Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q898A3 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: E63A047DC52F349B

FASTA30633,064
        10         20         30         40         50         60 
MMQSKIESII EECRKYTREG EVASYIPELK KADKDALGIY IDKLDGNEFC AGDYDTKFTI 

        70         80         90        100        110        120 
QSISKIIALI IAIMDNGMEK VLSKVGVEPS AYSFNSIVTL EVKNANKPLN PMINAGAIAT 

       130        140        150        160        170        180 
VSLIKGNSPE EIIERILEFT RKVTGNKNIK VNEEVYQSEK KTGDRNRSLA YFMKGTGIIE 

       190        200        210        220        230        240 
KDVEKVLDAY FQQCSIEVTC KDIAKIASFL ANDGVLPSTG ERIIPAEVAK IVKAVMVTCG 

       250        260        270        280        290        300 
MYDASGSFAV KVGIPSKSGV GGGILATVPG VMGIGVFGPA LDKKGNSIAG VKILERLSEE 


LNLSIF 

« Hide

References

[1]"The genome sequence of Clostridium tetani, the causative agent of tetanus disease."
Brueggemann H., Baeumer S., Fricke W.F., Wiezer A., Liesegang H., Decker I., Herzberg C., Martinez-Arias R., Merkl R., Henne A., Gottschalk G.
Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Massachusetts / E88.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015927 Genomic DNA. Translation: AAO35183.1.
RefSeqNP_781246.1. NC_004557.1.

3D structure databases

ProteinModelPortalQ898A3.
SMRQ898A3. Positions 2-306.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING212717.CTC00566.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO35183; AAO35183; CTC_00566.
GeneID1060847.
KEGGctc:CTC00566.
PATRIC19508958. VBICloTet101274_0529.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
KOK01425.
OMAMMDVSQI.
OrthoDBEOG6N94BK.

Enzyme and pathway databases

BioCycCTET212717:GJAM-509-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_CLOTE
AccessionPrimary (citable) accession number: Q898A3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families