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Q898A3

- GLSA_CLOTE

UniProt

Q898A3 - GLSA_CLOTE

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Protein
Glutaminase
Gene
glsA, CTC_00566
Organism
Clostridium tetani (strain Massachusetts / E88)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei62 – 621Substrate By similarity
Binding sitei114 – 1141Substrate By similarity
Binding sitei159 – 1591Substrate By similarity
Binding sitei166 – 1661Substrate By similarity
Binding sitei190 – 1901Substrate By similarity
Binding sitei242 – 2421Substrate By similarity
Binding sitei260 – 2601Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciCTET212717:GJAM-509-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:CTC_00566
OrganismiClostridium tetani (strain Massachusetts / E88)
Taxonomic identifieri212717 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001412: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306GlutaminaseUniRule annotation
PRO_0000110604Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi212717.CTC00566.

Structurei

3D structure databases

ProteinModelPortaliQ898A3.
SMRiQ898A3. Positions 2-306.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
KOiK01425.
OMAiMMDVSQI.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q898A3-1 [UniParc]FASTAAdd to Basket

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MMQSKIESII EECRKYTREG EVASYIPELK KADKDALGIY IDKLDGNEFC    50
AGDYDTKFTI QSISKIIALI IAIMDNGMEK VLSKVGVEPS AYSFNSIVTL 100
EVKNANKPLN PMINAGAIAT VSLIKGNSPE EIIERILEFT RKVTGNKNIK 150
VNEEVYQSEK KTGDRNRSLA YFMKGTGIIE KDVEKVLDAY FQQCSIEVTC 200
KDIAKIASFL ANDGVLPSTG ERIIPAEVAK IVKAVMVTCG MYDASGSFAV 250
KVGIPSKSGV GGGILATVPG VMGIGVFGPA LDKKGNSIAG VKILERLSEE 300
LNLSIF 306
Length:306
Mass (Da):33,064
Last modified:June 1, 2003 - v1
Checksum:iE63A047DC52F349B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015927 Genomic DNA. Translation: AAO35183.1.
RefSeqiNP_781246.1. NC_004557.1.

Genome annotation databases

EnsemblBacteriaiAAO35183; AAO35183; CTC_00566.
GeneIDi1060847.
KEGGictc:CTC00566.
PATRICi19508958. VBICloTet101274_0529.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015927 Genomic DNA. Translation: AAO35183.1 .
RefSeqi NP_781246.1. NC_004557.1.

3D structure databases

ProteinModelPortali Q898A3.
SMRi Q898A3. Positions 2-306.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 212717.CTC00566.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO35183 ; AAO35183 ; CTC_00566 .
GeneIDi 1060847.
KEGGi ctc:CTC00566.
PATRICi 19508958. VBICloTet101274_0529.

Phylogenomic databases

eggNOGi COG2066.
KOi K01425.
OMAi MMDVSQI.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci CTET212717:GJAM-509-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Massachusetts / E88.

Entry informationi

Entry nameiGLSA_CLOTE
AccessioniPrimary (citable) accession number: Q898A3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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