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Protein

Glutaminase

Gene

glsA

Organism
Clostridium tetani (strain Massachusetts / E88)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei62SubstrateUniRule annotation1
Binding sitei114SubstrateUniRule annotation1
Binding sitei159SubstrateUniRule annotation1
Binding sitei166SubstrateUniRule annotation1
Binding sitei190SubstrateUniRule annotation1
Binding sitei242SubstrateUniRule annotation1
Binding sitei260Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:CTC_00566
OrganismiClostridium tetani (strain Massachusetts / E88)
Taxonomic identifieri212717 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001412 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001106041 – 306GlutaminaseAdd BLAST306

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi212717.CTC00566.

Structurei

3D structure databases

ProteinModelPortaliQ898A3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
KOiK01425.
OMAiANYMKSF.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q898A3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMQSKIESII EECRKYTREG EVASYIPELK KADKDALGIY IDKLDGNEFC
60 70 80 90 100
AGDYDTKFTI QSISKIIALI IAIMDNGMEK VLSKVGVEPS AYSFNSIVTL
110 120 130 140 150
EVKNANKPLN PMINAGAIAT VSLIKGNSPE EIIERILEFT RKVTGNKNIK
160 170 180 190 200
VNEEVYQSEK KTGDRNRSLA YFMKGTGIIE KDVEKVLDAY FQQCSIEVTC
210 220 230 240 250
KDIAKIASFL ANDGVLPSTG ERIIPAEVAK IVKAVMVTCG MYDASGSFAV
260 270 280 290 300
KVGIPSKSGV GGGILATVPG VMGIGVFGPA LDKKGNSIAG VKILERLSEE

LNLSIF
Length:306
Mass (Da):33,064
Last modified:June 1, 2003 - v1
Checksum:iE63A047DC52F349B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015927 Genomic DNA. Translation: AAO35183.1.

Genome annotation databases

EnsemblBacteriaiAAO35183; AAO35183; CTC_00566.
KEGGictc:CTC_00566.
PATRICi19508958. VBICloTet101274_0529.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015927 Genomic DNA. Translation: AAO35183.1.

3D structure databases

ProteinModelPortaliQ898A3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi212717.CTC00566.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO35183; AAO35183; CTC_00566.
KEGGictc:CTC_00566.
PATRICi19508958. VBICloTet101274_0529.

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
KOiK01425.
OMAiANYMKSF.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_CLOTE
AccessioniPrimary (citable) accession number: Q898A3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: November 2, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.