ID   Q896V9_CLOTE            Unreviewed;       699 AA.
AC   Q896V9;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 105.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AAO35481.1};
GN   OrderedLocusNames=CTC_00888 {ECO:0000313|EMBL:AAO35481.1};
OS   Clostridium tetani (strain Massachusetts / E88).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=212717 {ECO:0000313|EMBL:AAO35481.1, ECO:0000313|Proteomes:UP000001412};
RN   [1] {ECO:0000313|EMBL:AAO35481.1, ECO:0000313|Proteomes:UP000001412}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Massachusetts / E88 {ECO:0000313|Proteomes:UP000001412};
RX   PubMed=12552129; DOI=10.1073/pnas.0335853100;
RA   Brueggemann H., Baumer S., Fricke W.F., Wiezer A., Liesegang H., Decker I.,
RA   Herzberg C., Martinez-Arias R., Merkl R., Henne A., Gottschalk G.;
RT   "The genome sequence of Clostridium tetani, the causative agent of tetanus
RT   disease.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE015927; AAO35481.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q896V9; -.
DR   STRING; 212717.CTC_00888; -.
DR   KEGG; ctc:CTC_00888; -.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   Proteomes; UP000001412; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd18773; PDC1_HK_sensor; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001412};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        14..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        321..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          341..393
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          412..662
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   699 AA;  77563 MW;  8D572E552FCB5FD8 CRC64;
     MREGIKIKSL KNKLVTISIF LVAIPVCLSI FISNYYMNKN LRPHIHEDHN ILSNTIANGV
     ADYMTKAYAL TEELISNDYV REFNAEKQNL AVKDAIKRNP YFDLFCIQNM KGDQTARSRG
     HLANRADRWW FKQSVKTKKP FVSKSYLTVN DNSEAINSII FPIIDNKGQM RGVMDADLKL
     DELQKMVEKY STDNTYAYVI DGNGAVIAHP NKEKVQEIYN YKTLQKTVRQ KDSSGKVIKD
     KNDVPVTKTE TIEVVDKLKE IVGLALTGKH GIVEYKDKDG EKVISSYGTI NLPGDSDNWA
     VITTQKEKDA FAMIYDIRNR IMIVGFIVLL LAIILSYIVS ARLIKPLTNL SELTQRAAKG
     DLTVKSDYHS EDEIGALSIS FNNMIDNMKA LIFNIKEVTE VVTNATESLL ASTQQTSSSI
     NEVAESMTNV AVDIEKGSEN AKDGVKSATD LSKELDSVSK KIVESEESSK NVYNISNNGF
     EVIRKLEEKN ERSSVVSREV TEVINSLSEK ANNIGTIVET INSISEETNL LALNAAIEAA
     RAGEAGKGFS VVAEEVRKLS ENTAESTNNV KSIISNIQKD IKLAQGTIKQ IEEVGIEQNE
     AVNITKDTFK EINTSIEGIV EKINTISESL FSVDSCKTNL ISVVEQVSFM AEGVAEATQN
     VCGATEEQNA EMEQISALAE DLNNMTQKLI GEVKSFKIE
//