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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Clostridium tetani (strain Massachusetts / E88)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:CTC_00966
OrganismiClostridium tetani (strain Massachusetts / E88)
Taxonomic identifieri212717 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001412 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515521 – 563Arginine--tRNA ligaseAdd BLAST563

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi212717.CTC00966.

Structurei

3D structure databases

ProteinModelPortaliQ896N5.
SMRiQ896N5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi120 – 130"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q896N5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYKELISER LSSIIELPIE DIEKLIEIPP KPEMGDFAFP CFQLAKTFRK
60 70 80 90 100
APNMIAEELK DKFDKSNFEK VENLGPYLNF FVDKSIFSKN VIEKILEEKD
110 120 130 140 150
KYGASNEGKG RKALIEYSSP NIAKPFHVGH LFSTAIGNAL YKIFTFEGYD
160 170 180 190 200
CERLNHLGDW GTQFGKLIAA YKRWVDEEAL EKEPIKELLR IYVKFHDEAE
210 220 230 240 250
KDPALEEEGR LHFKRLEDGE EEEVKLWKKF RELSLKEFEK VYHMLNVEFD
260 270 280 290 300
SYAGESFYGD KMDAVVEEID EKGLLVESNG AKVVMLEDYN MPPCIIKKSD
310 320 330 340 350
GATIYATRDL ATAIYRKKTY DFYKSIYVVG LEQSLHFKQV FTTLKLMGHD
360 370 380 390 400
WADDCTHIGF GLVRFTDRKL STRKGEVIFL EDLLKESVDK TLEIINEKNS
410 420 430 440 450
ELENKEETAK KIGIGAVIFT YLKNNRERDI VFSWDEMLSF DGETGPYVQY
460 470 480 490 500
SYARGKSILR KSGEIQGDVD YSKLNSKEEF ELVKTLEGFN KSILQAIEKL
510 520 530 540 550
EPSIVTRYVI EVAKAFNKFY NHNSILNAED EEIKKARIKL VESTCQVIKN
560
ALNLLGIEVV EKM
Length:563
Mass (Da):65,075
Last modified:June 1, 2003 - v1
Checksum:iC45B1DB7A9BFD9C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015927 Genomic DNA. Translation: AAO35555.1.
RefSeqiWP_011099217.1. NC_004557.1.

Genome annotation databases

EnsemblBacteriaiAAO35555; AAO35555; CTC_00966.
GeneIDi24254479.
KEGGictc:CTC_00966.

Similar proteinsi

Entry informationi

Entry nameiSYR_CLOTE
AccessioniPrimary (citable) accession number: Q896N5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: June 1, 2003
Last modified: August 30, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families