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Q89682 (MP1_MNSV) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Double gene block protein 1

Short name=DGBp1
Alternative name(s):
Movement protein P7A
Gene names
ORF Names:ORF2
OrganismMelon necrotic spot virus (MNSV)
Taxonomic identifier11987 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeCarmovirus
Virus hostCucumis melo (Muskmelon) [TaxID: 3656]
Cucumis sativus (Cucumber) [TaxID: 3659]

Protein attributes

Sequence length65 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Cell-to-cell movement. Displays RNA-binding activity. Ref.3

Subunit structure

Homodimer Probable.

Sequence similarities

Belongs to the carmovirus double gene block protein 1 family.

Ontologies

Keywords
   Biological processTransport
   LigandRNA-binding
   Molecular functionViral movement protein
Gene Ontology (GO)
   Biological_processtransmission of virus

Inferred from electronic annotation. Source: InterPro

transport of virus in host, cell to cell

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 6565Double gene block protein 1
PRO_0000398307

Regions

Region17 – 4327RNA-binding Probable

Experimental info

Mutagenesis13 – 197RGRSKER → AGASAEA: Complete loss of cell-to-cell movement ability. Ref.3
Mutagenesis25 – 273KQK → AQA: Complete loss of cell-to-cell movement ability. Ref.3
Mutagenesis32 – 332RK → AA: Complete loss of cell-to-cell movement ability. Drastic loss of RNA-binding activity.
Mutagenesis431K → A: 35% loss of cell-to-cell movement ability. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q89682 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 31030ADA243F318F

FASTA657,121
        10         20         30         40         50         60 
MDSQRTVELT NPRGRSKERG DSGGKQKNSM GRKIANDAIS ESKQGVMGAS TYIADKIKVT 


INFNF 

« Hide

References

[1]"Nucleotide sequence and genomic organization of melon necrotic spot virus."
Riviere C.J., Rochon D.M.
J. Gen. Virol. 71:1887-1896(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]"Genetic diversity of Melon necrotic spot virus and Olpidium isolates from different origins."
Herrera-Vasquez J.A., Cordoba-Selles M.C., Cebrian M.C., Rossello J.A., Alfaro-Fernandez A., Jorda C.
Plant Pathol. 59:240-251(2010)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
Strain: Isolate Spain/SP-13/2001.
[3]"A self-interacting carmovirus movement protein plays a role in binding of viral RNA during the cell-to-cell movement and shows an actin cytoskeleton dependent location in cell periphery."
Genoves A., Navarro J.A., Pallas V.
Virology 395:133-142(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, MUTAGENESIS OF 13-ARG--ARG-19; 25-LYS--LYS-27; 32-LYS-LYS-33 AND LYS-43.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D12536 Genomic RNA. Translation: BAA02102.1.
M29671 Genomic RNA. Translation: AAB02432.1.
FJ621526 Genomic RNA. Translation: ACT53373.1.
RefSeqNP_041229.1. NC_001504.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1491978.

Family and domain databases

InterProIPR007982. Tombusvirus_movement.
[Graphical view]
PfamPF05318. Tombus_movement. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMP1_MNSV
AccessionPrimary (citable) accession number: Q89682
Entry history
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: November 1, 1996
Last modified: January 22, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families