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Protein

Virion infectivity factor

Gene

vif

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Keywordsi

Biological processHost-virus interactionSAAS annotation, Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Virion infectivity factorUniRule annotation
Gene namesi
Name:vifImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Host cell membrane SAAS annotation; Peripheral membrane protein SAAS annotation; Cytoplasmic side SAAS annotation
  • Host cytoplasm SAAS annotation
  • Virion SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cell membraneSAAS annotation, Host cytoplasmSAAS annotation, Host membrane, Membrane, VirionSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the primate lentivirus group Vif protein family.SAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR000475. Viral_infect.
PfamiView protein in Pfam
PF00559. Vif. 1 hit.
PRINTSiPR00349. VIRIONINFFCT.

Sequencei

Sequence statusi: Complete.

Q89670-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENRWQVMIV WQVDRMRIRT WKSLVKHHMY VSKKAQGWWY RHHYDSPHPK
60 70 80 90 100
ISSEVHIPLG EARLVVKTYW GLHTGEREWH LGQGVSIEWR KKEYSTQVDP
110 120 130 140 150
GLADQLIHMY YFDCFAESAI RKAILGHIVS PRCDYQAGHN KVGSLQYLAL
160 170 180 190
TALIKPKKIK PPLPSVRKLT EDRWNKPQQT KGHRGSHTMN GH
Length:192
Mass (Da):22,609
Last modified:November 1, 1996 - v1
Checksum:i70C207AEABE1D468
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X91355 Genomic DNA. Translation: CAA62700.1.
X91357 Genomic DNA. Translation: CAA62702.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ89670_9HIV1
AccessioniPrimary (citable) accession number: Q89670
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: January 18, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)