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Protein

G-protein coupled receptor E1

Gene

E1

Organism
Equine herpesvirus 2 (strain 86/87) (EHV-2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
G-protein coupled receptor E1
Gene namesi
Name:E1
OrganismiEquine herpesvirus 2 (strain 86/87) (EHV-2)
Taxonomic identifieri82831 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeGammaherpesvirinaePercavirus
Virus hostiEquus caballus (Horse) [TaxID: 9796]
Proteomesi
  • UP000007083 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei13 – 35HelicalSequence analysisAdd BLAST23
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei109 – 129HelicalSequence analysisAdd BLAST21
Transmembranei160 – 180HelicalSequence analysisAdd BLAST21
Transmembranei190 – 210HelicalSequence analysisAdd BLAST21
Transmembranei242 – 262HelicalSequence analysisAdd BLAST21
Transmembranei279 – 299HelicalSequence analysisAdd BLAST21
Transmembranei323 – 343HelicalSequence analysisAdd BLAST21
Transmembranei351 – 371HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Host membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004059821 – 383G-protein coupled receptor E1Add BLAST383

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi145 ↔ 222PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliQ89609.
SMRiQ89609.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiVOG090000NY.

Family and domain databases

InterProiView protein in InterPro
IPR002236. Chemokine_CCR1.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00657. CCCHEMOKINER.
PR01106. CHEMOKINER1.
PR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q89609-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTSATSTV NTSSLATTMT TNFTSLLTSV VTTIASLVPS TNSSEDYYDD
60 70 80 90 100
LDDVDYEESA PCYKSDTTRL AAQVVPALYL LVFLFGLLGN ILVVIIVIRY
110 120 130 140 150
MKIKNLTNML LLNLAISDLL FLLTLPFWMH YIGMYHDWTF GISLCKLLRG
160 170 180 190 200
VCYMSLYSQV FCIILLTVDR YLAVVYAVTA LRFRTVTCGI VTCVCTWFLA
210 220 230 240 250
GLLSLPEFFF HGHQDDNGRV QCDPYYPEMS TNVWRRAHVA KVIMLSLILP
260 270 280 290 300
LLIMAVCYYV IIRRLLRRPS KKKYKAIRLI FVIMVAYFVF WTPYNIVLLL
310 320 330 340 350
STFHATLLNL QCALSSNLDM ALLITKTVAY THCCINPVIY AFVGEKFRRH
360 370 380
LYHFFHTYVA IYLCKYIPFL SGDGEGKEGP TRI
Length:383
Mass (Da):43,668
Last modified:November 1, 1996 - v1
Checksum:i0C65C53EAF539F72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20824 Genomic DNA. Translation: AAC13788.1.
U20824 Genomic DNA. Translation: AAC13866.1.
PIRiS55594.
RefSeqiNP_042597.1. NC_001650.2.
NP_042675.1. NC_001650.2.

Genome annotation databases

GeneIDi1461016.
1461067.
KEGGivg:1461016.
vg:1461067.

Similar proteinsi

Entry informationi

Entry nameiVGE1_EHV2
AccessioniPrimary (citable) accession number: Q89609
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: November 1, 1996
Last modified: October 25, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families