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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Clostridium tetani (strain Massachusetts / E88)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei38 – 381NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciCTET212717:GJAM-1174-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:CTC_01278
OrganismiClostridium tetani (strain Massachusetts / E88)
Taxonomic identifieri212717 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001412 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 289289tRNA pseudouridine synthase BPRO_0000121822Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi212717.CTC01278.

Structurei

3D structure databases

ProteinModelPortaliQ895J5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
KOiK03177.
OMAiDYSFLIP.
OrthoDBiPOG091H02G9.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q895J5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGVINVYKP QNITSFDVVR IIKKISRIKK VGHTGTLDPM ATGVLPICLG
60 70 80 90 100
GSTKIVDFIM NEHKEYRAKL KLGLITDTYD REGKVLKEED ASKILEEEVV
110 120 130 140 150
NCINSFKGEI IQIPPMYSAI KIKGERLYNL ARKGIEVERE GRKINIYNIE
160 170 180 190 200
VLKVNLPYVE FKVNCSKGTY IRSLCYDIGN KLGMGATMWE LERTKTGNFS
210 220 230 240 250
IENSINLEDI NEENIQEFII PAEKALSKYE RIEIDEYFSR LLKNGVKVKD
260 270 280
KRLLDKIKAN DILRVYQEDK FIGLGQKTKE GFKIVKLLV
Length:289
Mass (Da):33,102
Last modified:June 1, 2003 - v1
Checksum:iDCEE8C648F867BED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015927 Genomic DNA. Translation: AAO35845.1.
RefSeqiWP_011099507.1. NC_004557.1.

Genome annotation databases

EnsemblBacteriaiAAO35845; AAO35845; CTC_01278.
GeneIDi24254530.
KEGGictc:CTC_01278.
PATRICi19510511. VBICloTet101274_1303.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015927 Genomic DNA. Translation: AAO35845.1.
RefSeqiWP_011099507.1. NC_004557.1.

3D structure databases

ProteinModelPortaliQ895J5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi212717.CTC01278.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO35845; AAO35845; CTC_01278.
GeneIDi24254530.
KEGGictc:CTC_01278.
PATRICi19510511. VBICloTet101274_1303.

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
KOiK03177.
OMAiDYSFLIP.
OrthoDBiPOG091H02G9.

Enzyme and pathway databases

BioCyciCTET212717:GJAM-1174-MONOMER.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRUB_CLOTE
AccessioniPrimary (citable) accession number: Q895J5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.