ID   Q894K5_CLOTE            Unreviewed;       665 AA.
AC   Q894K5;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 108.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AAO36087.1};
GN   OrderedLocusNames=CTC_01536 {ECO:0000313|EMBL:AAO36087.1};
OS   Clostridium tetani (strain Massachusetts / E88).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=212717 {ECO:0000313|EMBL:AAO36087.1, ECO:0000313|Proteomes:UP000001412};
RN   [1] {ECO:0000313|EMBL:AAO36087.1, ECO:0000313|Proteomes:UP000001412}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Massachusetts / E88 {ECO:0000313|Proteomes:UP000001412};
RX   PubMed=12552129; DOI=10.1073/pnas.0335853100;
RA   Brueggemann H., Baumer S., Fricke W.F., Wiezer A., Liesegang H., Decker I.,
RA   Herzberg C., Martinez-Arias R., Merkl R., Henne A., Gottschalk G.;
RT   "The genome sequence of Clostridium tetani, the causative agent of tetanus
RT   disease.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE015927; AAO36087.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q894K5; -.
DR   STRING; 212717.CTC_01536; -.
DR   KEGG; ctc:CTC_01536; -.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   Proteomes; UP000001412; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd12913; PDC1_MCP_like; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 1.10.8.500; HAMP domain in histidine kinase; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001412};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        286..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          305..359
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          378..635
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          463..493
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   665 AA;  74010 MW;  E73A4DB22EFC7D69 CRC64;
     MDMKNRTIKK TLIIFIILCV VTPLTVISAI NFRYQSRSIK ENFENSVAQA MYSLSEDITN
     FKNTNSEIIN VLSDDYSSRT LVTDKNSEKL VQSNLNNLAK NHKEICVTYL GQATGKHYTT
     DKVDENYDPR KRPWYKSAIK DINNIAITEP YEDINKKGSF VITFAKVVKD LSNKPIGVAG
     IDIELEDLFN KVKNIKIGKD GFAVLIDNNG KILVSKDKGV IGKNVQDIKW ANNIIGDKKA
     VSNVDIEGEN YYACKIQNKD TLWHIMTLVP EKELKATLSK AKTTNVILGL VFLGISLLIA
     TIFLRNISKA IKKLTELMNK FGAGDFSQKI EEKDNDILEV KVIKRSINKM VENISSLIYE
     IKDTSDKLKI SAEDLAVITD EGSLAGDEVA EAIQRIAEGA LEQSKTLEDS VNWINKLRDE
     IKISLNNASV MSSSSDKVSE EVKKGNRVVN TLKNNFNHNI KSNNDLYEEI FSLEEEIKNI
     MNMANDIQDI TEQTNLLALN ASIEAAHAGE AGKGFAVVAE EVRNLAEQSS RATESINGIL
     NKIELKVKSI TLNIEEEKKL DDVTKESVNI TEASFKNIFD LTINLHENIE KTTNSLASIN
     NIKEEVTTRI AKVSFVSEET AASTEEVSAS TEEQASGLQE IASSAEILKG LSDDIKELIE
     SFKTV
//