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Protein

Virion infectivity factor

Gene

VIF

Organism
Simian immunodeficiency virus (SIV)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Host-virus interactionSAAS annotation, Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Virion infectivity factorUniRule annotation
Gene namesi
Name:VIFImported
Synonyms:VifImported, vifImported
OrganismiSimian immunodeficiency virus (SIV)Imported
Taxonomic identifieri11723 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiPan troglodytes (Chimpanzee) [TaxID: 9598]

Subcellular locationi

  • Host cell membrane SAAS annotation; Peripheral membrane protein SAAS annotation; Cytoplasmic side SAAS annotation
  • Host cytoplasm SAAS annotation
  • Virion SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Host cell membraneSAAS annotation, Host cytoplasmSAAS annotation, Host membrane, Membrane, VirionSAAS annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3RWIX-ray2.01C64-73[»]
3RWJX-ray2.70C66-73[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the primate lentivirus group Vif protein family.SAAS annotation

Family and domain databases

InterProiIPR000475. Viral_infect.
[Graphical view]
PfamiPF00559. Vif. 1 hit.
[Graphical view]
PRINTSiPR00349. VIRIONINFFCT.

Sequencei

Sequence statusi: Complete.

Q89490-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEEKRWIAV PTWRIPERLE RWHSLIKYLK YKTKDLQKVC YVPHFKVGWA
60 70 80 90 100
WWTCSRVIFP LQEGSHLEVQ GYWHLTPEKG WLSTYAVRIT WYSKNFWTDV
110 120 130 140 150
TPNYADILLH STYFPCFTAG EVRRAIRGEQ LLSCCRFPRA HKYQVPSLQY
160 170 180 190 200
LALKVVSDVR SQGENPTWKQ WRRDNRRGLR MAKQNSRGDK QRGGKPPTKG
210
ANFPGLAKVL GILA
Length:214
Mass (Da):25,267
Last modified:November 1, 1996 - v1
Checksum:i1C9C81F90D6DE17C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22792 Genomic DNA. Translation: AAA47642.1.
L22793 Genomic DNA. Translation: AAA47645.1.
L22796 Genomic DNA. Translation: AAA47654.1.
L22798 Genomic DNA. Translation: AAA47660.1.
L22799 Genomic DNA. Translation: AAA47663.1.
L22800 Genomic DNA. Translation: AAA47666.1.
L22803 Genomic DNA. Translation: AAA47675.1.
L22805 Genomic DNA. Translation: AAA47681.1.
L22806 Genomic DNA. Translation: AAA47684.1.
L22807 Genomic DNA. Translation: AAA47687.1.
AY576481 Genomic RNA. Translation: AAT72785.1.
AY597209 Genomic RNA. Translation: AAT97121.1.
AY603959 Genomic RNA. Translation: AAT99448.1.
AY600249 Genomic RNA. Translation: AAT99861.1.
AY599199 Genomic RNA. Translation: AAU14034.1.
AY599200 Genomic RNA. Translation: AAU14043.1.
AY599201 Genomic RNA. Translation: AAU14052.1.
AY611488 Genomic RNA. Translation: AAU94477.1.
AY588945 Genomic RNA. Translation: AAV65313.1.
AY588946 Genomic RNA. Translation: AAV65322.1.
AY587015 Genomic RNA. Translation: AAW32414.1.
KF439057 Genomic RNA. Translation: AGT48262.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22792 Genomic DNA. Translation: AAA47642.1.
L22793 Genomic DNA. Translation: AAA47645.1.
L22796 Genomic DNA. Translation: AAA47654.1.
L22798 Genomic DNA. Translation: AAA47660.1.
L22799 Genomic DNA. Translation: AAA47663.1.
L22800 Genomic DNA. Translation: AAA47666.1.
L22803 Genomic DNA. Translation: AAA47675.1.
L22805 Genomic DNA. Translation: AAA47681.1.
L22806 Genomic DNA. Translation: AAA47684.1.
L22807 Genomic DNA. Translation: AAA47687.1.
AY576481 Genomic RNA. Translation: AAT72785.1.
AY597209 Genomic RNA. Translation: AAT97121.1.
AY603959 Genomic RNA. Translation: AAT99448.1.
AY600249 Genomic RNA. Translation: AAT99861.1.
AY599199 Genomic RNA. Translation: AAU14034.1.
AY599200 Genomic RNA. Translation: AAU14043.1.
AY599201 Genomic RNA. Translation: AAU14052.1.
AY611488 Genomic RNA. Translation: AAU94477.1.
AY588945 Genomic RNA. Translation: AAV65313.1.
AY588946 Genomic RNA. Translation: AAV65322.1.
AY587015 Genomic RNA. Translation: AAW32414.1.
KF439057 Genomic RNA. Translation: AGT48262.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3RWIX-ray2.01C64-73[»]
3RWJX-ray2.70C66-73[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000475. Viral_infect.
[Graphical view]
PfamiPF00559. Vif. 1 hit.
[Graphical view]
PRINTSiPR00349. VIRIONINFFCT.
ProtoNetiSearch...

Entry informationi

Entry nameiQ89490_SIV
AccessioniPrimary (citable) accession number: Q89490
Secondary accession number(s): O12620, O12901
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.