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Protein

Gag polyprotein

Gene
N/A
Organism
Simian immunodeficiency virus (SIV)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingUniRule annotationSAAS annotation, Viral nucleoproteinUniRule annotation
Biological processHost-virus interaction, Viral budding, Viral budding via the host ESCRT complexesSAAS annotation, Viral release from host cell
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Gag polyproteinUniRule annotationSAAS annotation
OrganismiSimian immunodeficiency virus (SIV)Imported
Taxonomic identifieri11723 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiPan troglodytes (Chimpanzee) [TaxID: 9598]

Subcellular locationi

  • Virion UniRule annotation
  • Host nucleus UniRule annotation
  • Host cytoplasm UniRule annotation
  • Host cytoplasm UniRule annotationSAAS annotation
  • Host nucleus UniRule annotationSAAS annotation
  • Virion UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Capsid proteinUniRule annotationSAAS annotation, Host cytoplasmUniRule annotationSAAS annotation, Host nucleusUniRule annotationSAAS annotation, Virion

PTM / Processingi

Post-translational modificationi

Gag-Pol polyprotein: Specific enzymatic cleavages by the viral protease yield mature proteins.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ89464
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini393 – 408CCHC-typeInterPro annotationAdd BLAST16
Domaini415 – 430CCHC-typeInterPro annotationAdd BLAST16

Sequence similaritiesi

Belongs to the primate lentivirus group gag polyprotein family.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.1200.30, 1 hit
1.10.150.90, 1 hit
1.10.375.10, 1 hit
InterProiView protein in InterPro
IPR000721 Gag_p24
IPR000071 Lentvrl_matrix_N
IPR012344 Matrix_HIV/RSV_N
IPR008916 Retrov_capsid_C
IPR008919 Retrov_capsid_N
IPR010999 Retrovr_matrix
IPR001878 Znf_CCHC
IPR036875 Znf_CCHC_sf
PfamiView protein in Pfam
PF00540 Gag_p17, 1 hit
PF00607 Gag_p24, 1 hit
PF00098 zf-CCHC, 2 hits
PRINTSiPR00234 HIV1MATRIX
SMARTiView protein in SMART
SM00343 ZnF_C2HC, 2 hits
SUPFAMiSSF47836 SSF47836, 1 hit
SSF47943 SSF47943, 1 hit
SSF57756 SSF57756, 1 hit
PROSITEiView protein in PROSITE
PS50158 ZF_CCHC, 2 hits

Sequencei

Sequence statusi: Complete.

Q89464-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGARNSVLSG KKADELEKIR LRPGGKKRYK LKHIVWAANE LDRFGLAESL
60 70 80 90 100
LENKEGCQKI LSVLAPLVPT GSENLKSLYN TVCVLWCIHA EEKVKHTEEA
110 120 130 140 150
KQIVQRHLVV ETGTADKMPA TSRPTAPPSG KGGNYPVQQI GGNYTHLPLS
160 170 180 190 200
PRTLNAWVKL IEEKKFGAEV VPGFQALSEG CTPYDINQML NCVGEHQAAM
210 220 230 240 250
QIIREIINEE AADWDLQHPQ PGPIPPGQLR EPRGSDIAGT TSTVDEQIQW
260 270 280 290 300
MYRQQNPIPV GNIYRRWIQL GLQKCVRMYN PTNILDVKQG PKEPFQSYVD
310 320 330 340 350
RFYKSSRAEQ TDPAVKSWMT QTLLIQNANP DCKLVLKGLG INPTLEEMLT
360 370 380 390 400
ACQGVGGPGQ KARLMAEALK DALTQGPLPF AAVQQKGQRK IIKCWNCGKE
410 420 430 440 450
GHSARQCRAP RRQGCWKCGK AGHVMAKCPE RQAGFLGLGP WGKKPRNFPM
460 470 480 490 500
AQMPQGLTPT APPEDPAVDL LKNYMKMGRR QRENRERPYK EVTEDLLHLN

SLFGEDQ
Length:507
Mass (Da):56,614
Last modified:November 1, 1996 - v1
Checksum:iDEC118471EEF3833
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L09212 Genomic DNA Translation: AAA47566.1
L09213 Genomic DNA Translation: AAA47575.1
L09211 Genomic DNA Translation: AAA74697.1

Keywords - Coding sequence diversityi

Ribosomal frameshiftingSAAS annotation

Similar proteinsi

Entry informationi

Entry nameiQ89464_SIV
AccessioniPrimary (citable) accession number: Q89464
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health