ID   Q893I7_CLOTE            Unreviewed;       586 AA.
AC   Q893I7;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 104.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AAO36355.1};
GN   OrderedLocusNames=CTC_01835 {ECO:0000313|EMBL:AAO36355.1};
OS   Clostridium tetani (strain Massachusetts / E88).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=212717 {ECO:0000313|EMBL:AAO36355.1, ECO:0000313|Proteomes:UP000001412};
RN   [1] {ECO:0000313|EMBL:AAO36355.1, ECO:0000313|Proteomes:UP000001412}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Massachusetts / E88 {ECO:0000313|Proteomes:UP000001412};
RX   PubMed=12552129; DOI=10.1073/pnas.0335853100;
RA   Brueggemann H., Baumer S., Fricke W.F., Wiezer A., Liesegang H., Decker I.,
RA   Herzberg C., Martinez-Arias R., Merkl R., Henne A., Gottschalk G.;
RT   "The genome sequence of Clostridium tetani, the causative agent of tetanus
RT   disease.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE015927; AAO36355.1; -; Genomic_DNA.
DR   RefSeq; WP_011100015.1; NC_004557.1.
DR   AlphaFoldDB; Q893I7; -.
DR   STRING; 212717.CTC_01835; -.
DR   GeneID; 24253602; -.
DR   KEGG; ctc:CTC_01835; -.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   OrthoDB; 9810264at2; -.
DR   Proteomes; UP000001412; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR033480; sCache_2.
DR   PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF17200; sCache_2; 1.
DR   SMART; SM01049; Cache_2; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001412};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        208..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          231..280
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          299..563
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          559..586
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   586 AA;  66016 MW;  D4589C764E67D2EA CRC64;
     MTKHNKGLDK RLFKSYLGIF ILFFISILAV VLVSFIGAKG TLEKLGEEAL KNKINMGIEM
     MDMLETQVKN DNLAKEEAQE IFKNKMLNEK GNDGKTRGLN KKLELGIEAY MYAIDSNGIE
     KMHPFKEGEN ISNLVDNKGE NVTKLIIKEG KNPENGGLIT FWWKNPDEKQ TRKKVNAVAY
     YEPWDWYLNV GCYYEDFYGN IVDTFRNILI VAILILIMSI LLIRLMISKK VEPLNKVIEL
     IKKIGEGDLS SKVNINSKDE IGYMASTLNN ALDEIKSMVV SLKETSEKIN EKIKYVNEVT
     NTTSETSQNI TKAVEEIACS ATDTTKDMEI SFDAEKDLTD NIALIKDTSL LLQNEAMNAS
     KLNSNILNVL KNLEDKSIEN LNLSEETSKN MNILTDKSNT IIKIVNTIEN ISKQINLLAL
     NASIESSKAG VAGKGFAVVA QGIKELSEQT EQSTNHINQH VNELMKSILY SEESVNKTKK
     SSEIQRDTIK KTQNIFMEVI KFIEEVPKYI ENNVIRIEEV YNKNDTVNSS MDAVLGLMQG
     ISSATEEITS SMTEVNKSIL EINDMIDELG INANELNEKS QKFKIK
//