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Q891J1 (PYRF_CLOTE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:CTC_02381
OrganismClostridium tetani (strain Massachusetts / E88) [Complete proteome] [HAMAP]
Taxonomic identifier212717 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length288 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPyrimidine biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' UMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

'de novo' pyrimidine nucleobase biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionorotidine-5'-phosphate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 288288Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000066467

Sites

Active site971Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q891J1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: E3C843E0AB5E1F64

FASTA28832,456
        10         20         30         40         50         60 
MMIDKLYKRV EKNGHVCAGL DTSLDYIPEY FKTKYFNEED IIFNFNKEII DATYDKVACF 

        70         80         90        100        110        120 
KIQIAYYEAL GLKGLRAYKR TLDYIKESDG IVISDIKRGD ISSTAKMYAR AHFEGDFETD 

       130        140        150        160        170        180 
FITLSPYMGL DSIEPYFEYM KQKGKGVFVL VRTSNEGAKD IEFIESKDGN KVYEIIGKKL 

       190        200        210        220        230        240 
KNMGQDFLGN CGYSSIGGVV GCTHIDEAVK LRKDLGGMFF LIPGYGAQGG KAEDVALYLK 

       250        260        270        280 
NGNGGVVNSS RGILLAYKKQ NDEKNFAKCS RNEVIRMRDD ILQAINSK 

« Hide

References

[1]"The genome sequence of Clostridium tetani, the causative agent of tetanus disease."
Brueggemann H., Baeumer S., Fricke W.F., Wiezer A., Liesegang H., Decker I., Herzberg C., Martinez-Arias R., Merkl R., Henne A., Gottschalk G.
Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Massachusetts / E88.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015927 Genomic DNA. Translation: AAO36854.1.
RefSeqNP_782917.1. NC_004557.1.

3D structure databases

ProteinModelPortalQ891J1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING212717.CTC02381.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO36854; AAO36854; CTC_02381.
GeneID1060561.
KEGGctc:CTC02381.
PATRIC19512859. VBICloTet101274_2472.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
KOK01591.
OMAHIHARHP.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycCTET212717:GJAM-2189-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
ProtoNetSearch...

Entry information

Entry namePYRF_CLOTE
AccessionPrimary (citable) accession number: Q891J1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways