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Q88YH5

- PGK_LACPL

UniProt

Q88YH5 - PGK_LACPL

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei36 – 361SubstrateUniRule annotation
    Binding sitei119 – 1191SubstrateUniRule annotation
    Binding sitei160 – 1601SubstrateUniRule annotation
    Binding sitei211 – 2111ATPUniRule annotation
    Binding sitei329 – 3291ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi356 – 3594ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:lp_0790
    OrganismiLactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
    Taxonomic identifieri220668 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
    ProteomesiUP000000432: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 400400Phosphoglycerate kinasePRO_0000145956Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi220668.lp_0790.

    Structurei

    3D structure databases

    ProteinModelPortaliQ88YH5.
    SMRiQ88YH5. Positions 2-400.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni21 – 233Substrate bindingUniRule annotation
    Regioni59 – 624Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiWEALDIG.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q88YH5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKLIVSDLD VKDKKVLIRV DFNVPIKDGK IGDDNRIVAA LPTIKYVIEH    50
    DGKAILFSHL GRIKSEDDKK GLSLRPVAER LSNLLNKPVT FVPVTEGEQL 100
    ETAINNMNDG DVLVVENTRF EDVVNGEQVK RESGNDPELG KYWASLGDVY 150
    VNDAFGTAHR SHASNVGIAS NMDQVAAGFL MEKEIKFLGD AVDNPKHPFV 200
    AILGGAKVSD KIGVIDHLIS KADKIIIGGG MTYTFYAAKG MGIGNSLVEK 250
    DKIELAKSII EKAGDKLVLP SDSIVAEKFD NDVPSKVVEG SIPDGYMALD 300
    IGPKSIEEFE DVLRDAKTVV WNGPMGVFEM SNYAKGTLEI GKFLGTLSDA 350
    TTIVGGGDST AAVKQLGVGD KLTHISTGGG ASLEYLEGKE LPGIAAISEK 400
    Length:400
    Mass (Da):42,797
    Last modified:June 1, 2003 - v1
    Checksum:i1BD70A88477EF7A8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL935263 Genomic DNA. Translation: CCC78250.1.
    RefSeqiYP_004888764.1. NC_004567.2.

    Genome annotation databases

    EnsemblBacteriaiCCC78250; CCC78250; lp_0790.
    GeneIDi1063805.
    KEGGilpl:lp_0790.
    PATRICi22247991. VBILacPla27411_0667.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL935263 Genomic DNA. Translation: CCC78250.1 .
    RefSeqi YP_004888764.1. NC_004567.2.

    3D structure databases

    ProteinModelPortali Q88YH5.
    SMRi Q88YH5. Positions 2-400.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 220668.lp_0790.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CCC78250 ; CCC78250 ; lp_0790 .
    GeneIDi 1063805.
    KEGGi lpl:lp_0790.
    PATRICi 22247991. VBILacPla27411_0667.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi WEALDIG.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-793 / NCIMB 8826 / WCFS1.

    Entry informationi

    Entry nameiPGK_LACPL
    AccessioniPrimary (citable) accession number: Q88YH5
    Secondary accession number(s): F9UM11
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3