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Q88YH5 (PGK_LACPL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:lp_0790
OrganismLactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) [Reference proteome] [HAMAP]
Taxonomic identifier220668 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145956

Regions

Nucleotide binding356 – 3594ATP By similarity
Region21 – 233Substrate binding By similarity
Region59 – 624Substrate binding By similarity

Sites

Binding site361Substrate By similarity
Binding site1191Substrate By similarity
Binding site1601Substrate By similarity
Binding site2111ATP By similarity
Binding site3291ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q88YH5 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 1BD70A88477EF7A8

FASTA40042,797
        10         20         30         40         50         60 
MAKLIVSDLD VKDKKVLIRV DFNVPIKDGK IGDDNRIVAA LPTIKYVIEH DGKAILFSHL 

        70         80         90        100        110        120 
GRIKSEDDKK GLSLRPVAER LSNLLNKPVT FVPVTEGEQL ETAINNMNDG DVLVVENTRF 

       130        140        150        160        170        180 
EDVVNGEQVK RESGNDPELG KYWASLGDVY VNDAFGTAHR SHASNVGIAS NMDQVAAGFL 

       190        200        210        220        230        240 
MEKEIKFLGD AVDNPKHPFV AILGGAKVSD KIGVIDHLIS KADKIIIGGG MTYTFYAAKG 

       250        260        270        280        290        300 
MGIGNSLVEK DKIELAKSII EKAGDKLVLP SDSIVAEKFD NDVPSKVVEG SIPDGYMALD 

       310        320        330        340        350        360 
IGPKSIEEFE DVLRDAKTVV WNGPMGVFEM SNYAKGTLEI GKFLGTLSDA TTIVGGGDST 

       370        380        390        400 
AAVKQLGVGD KLTHISTGGG ASLEYLEGKE LPGIAAISEK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL935263 Genomic DNA. Translation: CCC78250.1.
RefSeqYP_004888764.1. NC_004567.2.

3D structure databases

ProteinModelPortalQ88YH5.
SMRQ88YH5. Positions 2-400.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING220668.lp_0790.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCC78250; CCC78250; lp_0790.
GeneID1063805.
KEGGlpl:lp_0790.
PATRIC22247991. VBILacPla27411_0667.

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAWEALDIG.

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_LACPL
AccessionPrimary (citable) accession number: Q88YH5
Secondary accession number(s): F9UM11
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2003
Last sequence update: June 1, 2003
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways