SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q88YE7

- GLMS_LACPL

UniProt

Q88YE7 - GLMS_LACPL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Gene
glmS, glmS1, lp_0822
Organism
Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source By similarity.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activity By similarity
Active sitei600 – 6001For Fru-6P isomerization activity By similarity

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciLPLA220668-WGS:GSPK-715-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC:2.6.1.16)
Alternative name(s):
D-fructose-6-phosphate amidotransferase
GFAT
Glucosamine-6-phosphate synthase
Hexosephosphate aminotransferase
L-glutamine--D-fructose-6-phosphate amidotransferase
Gene namesi
Name:glmS
Synonyms:glmS1
Ordered Locus Names:lp_0822
OrganismiLactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Taxonomic identifieri220668 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000000432: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 605604Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation
PRO_0000135344Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi220668.lp_0822.

Structurei

3D structure databases

ProteinModelPortaliQ88YE7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 220219Glutamine amidotransferase type-2
Add
BLAST
Domaini286 – 426141SIS 1
Add
BLAST
Domaini458 – 595138SIS 2
Add
BLAST

Sequence similaritiesi

Contains 2 SIS domains.

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
HOGENOMiHOG000258896.
KOiK00820.
OMAiGHKHTLA.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q88YE7-1 [UniParc]FASTAAdd to Basket

« Hide

MCGIVGVTGK DSAVSILLNG LEKLEYRGYD SAGIYVNDQD GHDYLVKEKG    50
RIDDLRKEVG EAVHGSTGIG HTRWATHGEP SVANAHPQVS ADGRFYLVHN 100
GVIENFEDLK QTYLSDVTFK SQTDTEVIVQ LVDRFVTKEG LSTLAAFRKT 150
LGLLGHSSYG FLLMDKEDPD TLYVAKNKSP LLIGVGEGFN VVCSDSLAML 200
DQTKDFLELH DGEIVVVKPD EIKITNQAGE PVERKPFHVD IDAAQADKGT 250
YPFYMLKEID EQPNVMRKLS QVYLNDAGDP IINDDLLTAL KAADRLYIVA 300
AGTSYHAGLV GAKLFESLAN VPTEVHVSSE FAYNQPLLSA HPFFIFLTQS 350
GETADSREVL LNVNDQHFPS LTITNVPNST LSREATYTLL LHAGPEIAVA 400
STKAYTAQIA LQAILAKALG VAVDQPAATA FDVKQQLALV ANGMQSLVDE 450
KATFEKIAKS ALLNTPNAFY IGRGLDYAVS LETALKLKEI SYVQAEGFAS 500
GELKHGTIAL IEKDTPVIGI ITQKNTAGLT RSNLQEVAAR GAKTVTIVTD 550
SLAKDGDTVI LPTVDERLTA LLSVVPGQLL AYYTSLNKGL DVDKPRNLAK 600
SVTVE 605
Length:605
Mass (Da):65,467
Last modified:January 23, 2007 - v2
Checksum:iE66D35D8127D7822
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL935263 Genomic DNA. Translation: CCC78279.1.
RefSeqiYP_004888793.1. NC_004567.2.

Genome annotation databases

EnsemblBacteriaiCCC78279; CCC78279; lp_0822.
GeneIDi1063937.
KEGGilpl:lp_0822.
PATRICi22248051. VBILacPla27411_0697.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL935263 Genomic DNA. Translation: CCC78279.1 .
RefSeqi YP_004888793.1. NC_004567.2.

3D structure databases

ProteinModelPortali Q88YE7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 220668.lp_0822.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCC78279 ; CCC78279 ; lp_0822 .
GeneIDi 1063937.
KEGGi lpl:lp_0822.
PATRICi 22248051. VBILacPla27411_0697.

Phylogenomic databases

eggNOGi COG0449.
HOGENOMi HOG000258896.
KOi K00820.
OMAi GHKHTLA.

Enzyme and pathway databases

BioCyci LPLA220668-WGS:GSPK-715-MONOMER.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-793 / NCIMB 8826 / WCFS1.

Entry informationi

Entry nameiGLMS_LACPL
AccessioniPrimary (citable) accession number: Q88YE7
Secondary accession number(s): F9UM40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi