Reviewed, UniProtKB/Swiss-Prot Q88W33 (MSRB_LACPL)

Names and origin

Protein names

Recommended name:
    Peptide methionine sulfoxide reductase msrB
    EC=1.8.4.12
Alternative name(s):
    Peptide-methionine (R)-S-oxide reductase

Gene names

Name:	msrB
Synonyms:	msrA3
Ordered Locus Names:	lp_1836

Organism

Lactobacillus plantarum [Complete proteome] [HAMAP]

Taxonomic identifier

1590 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	144 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Sequence similarities	Belongs to the msrB Met sulfoxide reductase family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 144	144	Peptide methionine sulfoxide reductase msrB HAMAP MF_01400		PRO_0000140277
Sites
	Active site	117	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q88W33-1 [UniParc]. Last modified June 16, 2003. Version 1. Checksum: CAD30DDCC2E59248	FASTA	144	16,278
	10 20 30 40 50 60 MDKQQGELRQ RLTPEQYAVT QEAATERPFS GEYDNFYQEG IYVDVVSGQA LFSSRDKYDA 70 80 90 100 110 120 GCGWPSFTKP IDQTNLNEHR DESFGMHRTE VTSTQANSHL GHVFPDGPRD RGGLRYCINS 130 140 AALKFIPVAD LEKAGYGQYQ SLFK

References

[1]

"Complete genome sequence of Lactobacillus plantarum WCFS1." Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P., Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J., Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M., Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M., Siezen R.J. Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003) [PubMed: 12566566] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-793 / NCIMB 8826 / WCFS1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL935257 Genomic DNA. Translation: CAD64238.1.
RefSeq	NP_785389.1.
3D structure databases
HSSP	HSSP built from PDB template 1L1D based on UniProtKB P14930.
ModBase	Search...
Genome annotation databases
GeneID	1063073.
GenomeReviews	Gene locus lp_1836 in contig AL935263_GR.
KEGG	lpl:lp_1836.
NMPDR	fig|220668.1.peg.1523.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q88W33.
OMA	Q88W33. KYESGCG.
Enzyme and pathway databases
BioCyc	LPLA220668:LP_1836-MON.
BRENDA	1.8.4.12. 593.
Family and domain databases
HAMAP	MF_01400. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
ProDom	PD004057. DUF25. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00357. MsrB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSRB_LACPL

Accession

Primary (citable) accession number: Q88W33

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 16, 2003
Last sequence update:	June 16, 2003
Last modified:	June 16, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)