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Protein

Glutamate racemase

Gene

murI

Organism
Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Provides the (R)-glutamate required for cell wall biosynthesis.UniRule annotation

Catalytic activityi

L-glutamate = D-glutamate.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei74 – 741Proton donor/acceptorUniRule annotation
Active sitei185 – 1851Proton donor/acceptorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciLPLA220668-WGS:GSPK-1961-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate racemaseUniRule annotation (EC:5.1.1.3UniRule annotation)
Gene namesi
Name:murIUniRule annotation
Ordered Locus Names:lp_2268
OrganismiLactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Taxonomic identifieri220668 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000000432 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 273273Glutamate racemasePRO_0000095481Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi220668.lp_2268.

Structurei

3D structure databases

ProteinModelPortaliQ88V19.
SMRiQ88V19. Positions 2-268.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni11 – 122Substrate bindingUniRule annotation
Regioni43 – 442Substrate bindingUniRule annotation
Regioni75 – 762Substrate bindingUniRule annotation
Regioni186 – 1872Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the aspartate/glutamate racemases family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105F03. Bacteria.
COG0796. LUCA.
HOGENOMiHOG000262396.
KOiK01776.
OMAiVPYGSKS.

Family and domain databases

Gene3Di3.40.50.1860. 1 hit.
HAMAPiMF_00258. Glu_racemase. 1 hit.
InterProiIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS_1.
IPR033134. Asp/Glu_racemase_AS_2.
IPR004391. Glu_race.
[Graphical view]
PfamiPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMiSSF53681. SSF53681. 2 hits.
TIGRFAMsiTIGR00067. glut_race. 1 hit.
PROSITEiPS00923. ASP_GLU_RACEMASE_1. 1 hit.
PS00924. ASP_GLU_RACEMASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q88V19-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANEHAIGFM DSGVGGLTVV KQALKQLPRE TVYFIGDQAR LPYGPRPAEQ
60 70 80 90 100
VRTFSFQMAD FLMAKQIKML VIACNTATAA ALPALRQQLS IPVIGVIAPG
110 120 130 140 150
SRAALKASHR NRIGVIATEG TIRSNAYRDA ILTKDPTATV VSQACPKFVP
160 170 180 190 200
LVESNEYQST VAKRVVAETL KQLKKQDVDT LVLGCTHYPL LRPLIQNVMG
210 220 230 240 250
PGVTLIDSGA ETVNDVSAVL DYLDIANDRS TKRYPDEYYT TGAADQFEAI
260 270
ARNWLGQPDF HAQHIDLGSE AND
Length:273
Mass (Da):29,713
Last modified:June 1, 2003 - v1
Checksum:i201F79C1A2570763
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935263 Genomic DNA. Translation: CCC79476.1.
RefSeqiWP_003644631.1. NC_004567.2.
YP_004889990.1. NC_004567.2.

Genome annotation databases

EnsemblBacteriaiCCC79476; CCC79476; lp_2268.
GeneIDi1062262.
KEGGilpl:lp_2268.
PATRICi22250607. VBILacPla27411_1919.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935263 Genomic DNA. Translation: CCC79476.1.
RefSeqiWP_003644631.1. NC_004567.2.
YP_004889990.1. NC_004567.2.

3D structure databases

ProteinModelPortaliQ88V19.
SMRiQ88V19. Positions 2-268.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi220668.lp_2268.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCC79476; CCC79476; lp_2268.
GeneIDi1062262.
KEGGilpl:lp_2268.
PATRICi22250607. VBILacPla27411_1919.

Phylogenomic databases

eggNOGiENOG4105F03. Bacteria.
COG0796. LUCA.
HOGENOMiHOG000262396.
KOiK01776.
OMAiVPYGSKS.

Enzyme and pathway databases

UniPathwayiUPA00219.
BioCyciLPLA220668-WGS:GSPK-1961-MONOMER.

Family and domain databases

Gene3Di3.40.50.1860. 1 hit.
HAMAPiMF_00258. Glu_racemase. 1 hit.
InterProiIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS_1.
IPR033134. Asp/Glu_racemase_AS_2.
IPR004391. Glu_race.
[Graphical view]
PfamiPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMiSSF53681. SSF53681. 2 hits.
TIGRFAMsiTIGR00067. glut_race. 1 hit.
PROSITEiPS00923. ASP_GLU_RACEMASE_1. 1 hit.
PS00924. ASP_GLU_RACEMASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMURI_LACPL
AccessioniPrimary (citable) accession number: Q88V19
Secondary accession number(s): F9UQI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2003
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.