Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q88UU5

- MURA1_LACPL

UniProt

Q88UU5 - MURA1_LACPL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1

Gene

murA1

Organism
Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.UniRule annotation

Catalytic activityi

Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei119 – 1191Proton donorUniRule annotation

GO - Molecular functioni

  1. UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. cell wall organization Source: UniProtKB-KW
  4. peptidoglycan biosynthetic process Source: UniProtKB-HAMAP
  5. regulation of cell shape Source: UniProtKB-KW
  6. UDP-N-acetylgalactosamine biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Cell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Keywords - Ligandi

Pyruvate

Enzyme and pathway databases

BioCyciLPLA220668-WGS:GSPK-2034-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1UniRule annotation (EC:2.5.1.7UniRule annotation)
Alternative name(s):
Enoylpyruvate transferase 1UniRule annotation
UDP-N-acetylglucosamine enolpyruvyl transferase 1UniRule annotation
Short name:
EPT 1UniRule annotation
Gene namesi
Name:murA1UniRule annotation
Ordered Locus Names:lp_2361
OrganismiLactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Taxonomic identifieri220668 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000000432: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 438438UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1PRO_0000178881Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei119 – 11912-(S-cysteinyl)pyruvic acid O-phosphothioketalUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi220668.lp_2361.

Structurei

3D structure databases

ProteinModelPortaliQ88UU5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the EPSP synthase family. MurA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0766.
HOGENOMiHOG000075602.
KOiK00790.
OMAiVTDIYHI.

Family and domain databases

Gene3Di3.65.10.10. 2 hits.
HAMAPiMF_00111. MurA.
InterProiIPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view]
PANTHERiPTHR21090:SF4. PTHR21090:SF4. 1 hit.
PfamiPF00275. EPSP_synthase. 1 hit.
[Graphical view]
SUPFAMiSSF55205. SSF55205. 1 hit.
TIGRFAMsiTIGR01072. murA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q88UU5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEEIVVHGGQ RLTGNVHIEG AKNAVLPILA ASLLASSGQT HLSNVPVLSD
60 70 80 90 100
VFTMNNVLKF LNTKIDFDEI NKTIDIDASR QLSSEAPFQY VSKMRASIVV
110 120 130 140 150
MGPLLARLGH AKVAMPGGCA IGSRPIDLHL KGLNALGAEI ERHDGYVEAT
160 170 180 190 200
ANQLHGAAIY LDFPSVGATQ NIMMAATLAD GITTMENVAR EPEIVDLANY
210 220 230 240 250
LNQMGAKVTG AGTETIRIEG VKAMHGCDHS IVQDRIEAGT FMVAAAVTQG
260 270 280 290 300
NVLVEDAIAE HNKPLISKMR EMGVTVTEEP AGIRVIGPEI LKPTSVKTMP
310 320 330 340 350
HPGFPTDMQP QMTILQLCAQ GTSLLTETVF ENRFMHLDEL RRMNADFKVE
360 370 380 390 400
GRSVIMYGPT DFNGAQVTAT DLRAAAALVI AGLVSRGYTE VTNLKYLDRG
410 420 430
YFNFHGKLAK LGAEIKRVDV PDGTVYALNP DFANEAAE
Length:438
Mass (Da):47,147
Last modified:June 1, 2003 - v1
Checksum:iE48B4C5686B3A8AA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL935263 Genomic DNA. Translation: CCC79550.1.
RefSeqiYP_004890064.1. NC_004567.2.

Genome annotation databases

EnsemblBacteriaiCCC79550; CCC79550; lp_2361.
GeneIDi1062393.
KEGGilpl:lp_2361.
PATRICi22250759. VBILacPla27411_1995.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL935263 Genomic DNA. Translation: CCC79550.1 .
RefSeqi YP_004890064.1. NC_004567.2.

3D structure databases

ProteinModelPortali Q88UU5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 220668.lp_2361.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCC79550 ; CCC79550 ; lp_2361 .
GeneIDi 1062393.
KEGGi lpl:lp_2361.
PATRICi 22250759. VBILacPla27411_1995.

Phylogenomic databases

eggNOGi COG0766.
HOGENOMi HOG000075602.
KOi K00790.
OMAi VTDIYHI.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci LPLA220668-WGS:GSPK-2034-MONOMER.

Family and domain databases

Gene3Di 3.65.10.10. 2 hits.
HAMAPi MF_00111. MurA.
InterProi IPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view ]
PANTHERi PTHR21090:SF4. PTHR21090:SF4. 1 hit.
Pfami PF00275. EPSP_synthase. 1 hit.
[Graphical view ]
SUPFAMi SSF55205. SSF55205. 1 hit.
TIGRFAMsi TIGR01072. murA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-793 / NCIMB 8826 / WCFS1.

Entry informationi

Entry nameiMURA1_LACPL
AccessioniPrimary (citable) accession number: Q88UU5
Secondary accession number(s): F9UQR1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2003
Last sequence update: June 1, 2003
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3