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Q88UI4 (G6PI_LACPL) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:lp_2502
OrganismLactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) [Reference proteome] [HAMAP]
Taxonomic identifier220668 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 450450Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180659

Sites

Active site2901Proton donor By similarity
Active site3111 By similarity
Active site4251 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q88UI4 [UniParc].

Last modified May 23, 2003. Version 1.
Checksum: 99DFCC7CF7A3E5D1

FASTA45049,847
        10         20         30         40         50         60 
MAHISFDSSN LTKFVHNNEL GEMQAMVTAA DKELREGTGA GNDFRGWLNL PTDYDKEEFA 

        70         80         90        100        110        120 
RIKTAAKKIQ DDSDVLVVIG IGGSYLGARA AIEFLHETFW SSLSREDRKF PQVVFAGNSI 

       130        140        150        160        170        180 
SSSYVNDLIH LIGDRDFSVN IISKSGTTTE PSIAFRVFKE RLIAKYGEEA AKGRIYATTD 

       190        200        210        220        230        240 
RKRGALKQEA DAEGYETFVI PDDVGGRFTV LTPVGLLPIA VSGGDIDSLM KGAADAQNEY 

       250        260        270        280        290        300 
KDADLSKNEA YQYAAYRNIL YRKGYTTEIL ENYEPNMAMF SEWWKQLMGE SEGKDQKGIY 

       310        320        330        340        350        360 
PSSANFTTDL HSLGQYIQEG RRNLMETVVK VDNATSDVDI PKETENLDGL KYLEGKTMAQ 

       370        380        390        400        410        420 
VNTKAFEGVI MAHVDGGVPN MVVNIPSQDA YTLGYTMYFF EAAVAISGYL NGINPFNQPG 

       430        440        450 
VEAYKNNMFA LLGKPGYEEL TKKLTARLSD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL935263 Genomic DNA. Translation: CCC79670.1.
RefSeqYP_004890184.1. NC_004567.2.

3D structure databases

ProteinModelPortalQ88UI4.
SMRQ88UI4. Positions 3-448.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING220668.lp_2502.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCC79670; CCC79670; lp_2502.
GeneID1062659.
KEGGlpl:lp_2502.
PATRIC22250999. VBILacPla27411_2107.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000100403.
KOK01810.
OMAKNMTHIT.

Enzyme and pathway databases

BioCycLPLA220668-WGS:GSPK-2162-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_LACPL
AccessionPrimary (citable) accession number: Q88UI4
Secondary accession number(s): F9UR31
Entry history
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: May 23, 2003
Last modified: July 9, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways