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Protein

Probable D-serine dehydratase

Gene

dsdA

Organism
Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-serine = pyruvate + NH3.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciLPLA220668-WGS:GSPK-2375-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable D-serine dehydrataseUniRule annotation (EC:4.3.1.18UniRule annotation)
Alternative name(s):
D-serine deaminaseUniRule annotation
Short name:
DSDUniRule annotation
Gene namesi
Name:dsdAUniRule annotation
Ordered Locus Names:lp_2776
OrganismiLactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Taxonomic identifieri220668 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000000432 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 436436Probable D-serine dehydratasePRO_0000185615Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei111 – 1111N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi220668.lp_2776.

Structurei

3D structure databases

ProteinModelPortaliQ88TY1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serine/threonine dehydratase family. DsdA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZC. Bacteria.
COG3048. LUCA.
HOGENOMiHOG000218072.
KOiK01753.
OMAiHCLFAEP.

Family and domain databases

HAMAPiMF_01030. D_Ser_dehydrat.
InterProiIPR011780. D_Ser_am_lyase.
IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PANTHERiPTHR10314:SF9. PTHR10314:SF9. 2 hits.
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR02035. D_Ser_am_lyase. 1 hit.
PROSITEiPS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q88TY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTTVMIEEH PQIKELIAKR PIVWQNPDYG KRADLPLTRA DIFDAVARWE
60 70 80 90 100
RFAPFLAVAF PETAAMNGII ESPLLPLEQM KPAWEALNHQ SLAGQLYLKA
110 120 130 140 150
DSQLPISGSI KSRGGIYEVL KFAEQVAMAH TDLTYMDDYS VLATAKYHEL
160 170 180 190 200
FAQYGVIVAS TGNLALSVGI MAATFGFKTT VYMSHDARQW KKDKLRANGV
210 220 230 240 250
TVEELNTDFS SVIPVARAAA AKDDHTHFVD DEGSRDLFLG YAVAGVRLQH
260 270 280 290 300
QLKVQGIKMD AAHPVVVYLP AGVGGSPSGV AFGLKMIMGA NIYPVFCEPT
310 320 330 340 350
HVPSVTLGMM TKLNEKIAVQ DIGLDGLTAA DGLAVSRPSR LAGKVMRTLL
360 370 380 390 400
LGTATFEDDD LYRYLTKLVD TEDVIVEPSA AAGFTAIAPI MAQFPTLAGK
410 420 430
DVTHIVWATG GDMMPESERQ LDYELGQKLL TKINNR
Length:436
Mass (Da):47,572
Last modified:June 1, 2003 - v1
Checksum:i2A74F012004530FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935263 Genomic DNA. Translation: CCC79884.1.
RefSeqiWP_011101913.1. NC_004567.2.
YP_004890398.1. NC_004567.2.

Genome annotation databases

EnsemblBacteriaiCCC79884; CCC79884; lp_2776.
GeneIDi1063115.
KEGGilpl:lp_2776.
PATRICi22251433. VBILacPla27411_2324.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935263 Genomic DNA. Translation: CCC79884.1.
RefSeqiWP_011101913.1. NC_004567.2.
YP_004890398.1. NC_004567.2.

3D structure databases

ProteinModelPortaliQ88TY1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi220668.lp_2776.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCC79884; CCC79884; lp_2776.
GeneIDi1063115.
KEGGilpl:lp_2776.
PATRICi22251433. VBILacPla27411_2324.

Phylogenomic databases

eggNOGiENOG4105BZC. Bacteria.
COG3048. LUCA.
HOGENOMiHOG000218072.
KOiK01753.
OMAiHCLFAEP.

Enzyme and pathway databases

BioCyciLPLA220668-WGS:GSPK-2375-MONOMER.

Family and domain databases

HAMAPiMF_01030. D_Ser_dehydrat.
InterProiIPR011780. D_Ser_am_lyase.
IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PANTHERiPTHR10314:SF9. PTHR10314:SF9. 2 hits.
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR02035. D_Ser_am_lyase. 1 hit.
PROSITEiPS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-793 / NCIMB 8826 / WCFS1.

Entry informationi

Entry nameiSDHD_LACPL
AccessioniPrimary (citable) accession number: Q88TY1
Secondary accession number(s): F9URP5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: June 1, 2003
Last modified: November 11, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.